摘要
目的:观察茵栀黄口服液联合蓝光照射及枯草杆菌肠球菌二联活菌散剂治疗新生儿黄疸的疗效,并分析该联合疗法对患儿肝功能的影响。方法:回顾性分析100例新生儿黄疸患儿的临床资料,按照不同治疗方案分为常规治疗组和茵栀黄治疗组各50例。常规治疗组予以蓝光照射及枯草杆菌肠球菌二联活菌散剂治疗;茵栀黄治疗组在常规治疗组基础上给予茵栀黄口服液口服治疗。2组均治疗7 d。比较2组临床疗效、住院时间、胎便排空时间及不良反应发生情况,比较2组治疗前后胆红素和肝功能指标水平。结果:茵栀黄治疗组总有效率96.00%,高于常规治疗组84.00%(P<0.05)。治疗后,2组血清直接胆红素(DBil)、间接胆红素(IBil)、总胆红素(TBil)水平均下降(P<0.05),且茵栀黄治疗组低于常规治疗组(P<0.05)。治疗后,2组血清谷氨酸氨基转移酶(AST)、丙氨酸氨基转移酶(ALT)及碱性磷酸酶(ALP)水平均降低(P<0.05),且茵栀黄治疗组低于常规治疗组(P<0.05)。茵栀黄治疗组患儿的住院时间、胎便排空时间均短于常规治疗组(P<0.05)。2组不良反应总发生率比较,差异无统计学意义(P>0.05)。结论:采用茵栀黄口服液联合蓝光照射及枯草杆菌肠球菌二联活菌散剂治疗新生儿黄疸能够提高临床疗效,保护患儿肝功能,降低胆红素水平和不良反应的发生。
Objective:To observe the curative effect of Yinzhihuang Oral Liquid combined with blue light and Live Combined Bacilus Subtilis and Enterococcus Faecium Powder for neonatal jaundice,and to analyze the effect of the combined therapy for liver function in children.Methods:The clinical data of 100 cases of neonatal jaundice was given retrospective analysis,and the patients were divided into the routine treatment group and the Yinzhihuang treatment group according to different treatment plans,with 50 cases in each group.The routine treatment group was treated with blue light and Live Combined Bacilus Subtilis and Enterococcus Faecium Powder,and the Yinzhihuang treatment group was additionally treated with Yinzhihuang Oral Liquid based on the treatment of the routine treatment group.Both groups were treated for 7 days.The clinical effects,hospitalization time,fecal emptying time,and incidence of adverse reactions were compared between the two groups.The levels of bilirubin and liver function indicators in the two groups were compared before and after treatment.Results:The total effective rate was 96.00%in the Yinzhihuang treatment group,lower than that of 84.00%in the routine treatment group(P<0.05).After treatment,the levels of direct bilirubin(DBil),indirect bilirubin(IBil),and total bilirubin(TBil)in serum in the two groups were decreased(P<0.05),and the levels in the Yinzhihuang treatment group were lower than those in the routine treatment group(P<0.05).After treatment,the levels of aspartate aminotransferase(AST),alanine aminotransferase(ALT),and alkaline phosphatase(ALP)in serum in the two groups were decreased(P<0.05),and the levels in the Yinzhihuang treatment group were lower than those in the routine treatment group(P<0.05).The hospitalization time and fecal emptying time in the Yinzhihuang treatment group were shorter than those in the routine treatment group(P<0.05).There was no significant difference in the total incidence of adverse reactions between the two groups(P>0.05).Conclusion:The application of
作者
常晓雯
赵燕凤
CHANG Xiaowen;ZHAO Yanfeng(Department of Neonatology,Hangzhou Women's Hospital,Hangzhou Zhejiang 310000,China)
出处
《新中医》
CAS
2024年第1期130-134,共5页
New Chinese Medicine
关键词
新生儿黄疸
茵栀黄口服液
枯草杆菌肠球菌二联活菌散剂
胆红素
肝功能
Neonatal jaundice
Yinzhihuang Oral Liquid
Live Combined Bacilus Subtilis and Enterococcus Faecium Powder
Bilirubin
Liver function
