摘要
目的:观察扶正除伏汤联合克林霉素磷酸酯片治疗盆腔炎性疾病后遗症(SPID)的临床疗效。方法:选取88例SPID患者,按随机数字表法分为对照组和观察组各44例。对照组给予克林霉素磷酸酯片治疗,观察组在对照组基础上给予扶正除伏汤治疗。比较2组治疗前后中医证候积分、炎性包块最大直径、盆腔积液深度、炎性因子水平及血液流变学指标变化。结果:治疗后,2组下腹痛、带下量多、月经不调、肢体乏力评分均较治疗前降低(P<0.05),且观察组各项评分均低于对照组(P<0.05)。治疗后,2组炎性包块最大直径及盆腔积液深度均较治疗前减小(P<0.05),且观察组炎性包块最大直径及盆腔积液深度均低于对照组(P<0.05)。治疗后,2组血清肿瘤坏死因子-α(TNF-α)、白细胞介素-6(IL-6)水平均较治疗前下降(P<0.05),且观察组TNF-α、IL-6水平低于对照组(P<0.05)。治疗后,2组血浆黏度、全血黏度、纤维蛋白原含量及红细胞沉降率均较治疗前降低(P<0.05),且观察组各项指标均低于对照组(P<0.05)。结论:扶正除伏汤联合克林霉素磷酸酯片治疗SPID患者可以有效改善临床症状,降低炎症反应,调节血液黏滞状态,治疗效果优于单纯抗菌药物。
Objective:To observe the clinical effect of Fuzheng Chufu Decoction combined with Clindamycin Phosphate Tablets for sequelae of pelvic inflammatory disease(SPID).Methods:A total of 88 SPID patients were selected and divided into the control group and the observation group according to the random number table method,with 44 patients in each group.The control group was treated with Clindamycin Phosphate Tablets,and the observation group was treated with Fuzheng Chufu Decoction based on the treatment of the control group.The changes in traditional Chinese medicine syndrome scores,maximum diameter of inflammatory mass,depth of pelvic fluid accumulation,levels of inflammatory factors,and hemorheological indicators were compared between the two groups before and after treatment.Results:After treatment,the scores of lower abdominal pain,excessive vaginal discharge,irregular menstruation,limb fatigue in the two groups were decreased when compared with those before treatment(P<0.05),and the above scores in the observation group were lower than those in the control group(P<0.05).After treatment,the maximum diameter of inflammatory masses and the depth of pelvic fluid accumulation in the two groups were decreased when compared with those before treatment(P<0.05),and the maximum diameter of inflammatory masses and the depth of pelvic fluid accumulation in the observation group were lower than those in the control group(P<0.05).After treatment,the levels of tumor necrosis factor-α(TNF-α)and interleukin-6(IL-6)in serum in the two groups were decreased when compared with those before treatment(P<0.05),and the levels of TNF-αand IL-6 in the observation group were lower than those in the control group(P<0.05).After treatment,the plasma viscosity,whole blood viscosity,fibrinogen content,and erythrocyte sedimentation rates in the two groups were decreased when compared with those before treatment(P<0.05),and the above indexes in the observation group were lower than those in the control group(P<0.05).Conclusion:Fuzheng Chufu Dec
作者
周辉
郝玉娟
邢秋丽
ZHOU Hui;HAO Yujuan;XING Qiuli(Department of Obstetrics and Gynecology,Xuchang Central Hospital,Xuchang Henan 461000,China)
出处
《新中医》
CAS
2024年第1期108-112,共5页
New Chinese Medicine
关键词
盆腔炎性疾病后遗症
扶正除伏汤
克林霉素磷酸酯片
膜原学说
炎性因子
血液流变学
Sequelae of pelvic inflammatory disease
Fuzheng Chufu Decoction
Clindamycin Phosphate Tablets
Membrane-source theory
Inflammatory factors
Hemorheology
