摘要
目的:初步探讨新辅助治疗联合机器人胃癌根治术治疗进展期SiewertⅡ、Ⅲ型食管胃结合部腺癌的安全性与可行性。方法:回顾分析2018年1月至2023年11月为15例进展期SiewertⅡ、Ⅲ型食管胃结合部腺癌患者行新辅助治疗联合机器人胃癌根治术的临床资料。结果:15例手术均获成功,无一例中转开腹。患者接受新辅助治疗2~5个周期,治疗结束至手术间隔4(2,5)周。新辅助治疗后患者肿瘤缓解率73.3%,手术时间305(280,367)min,术中出血量200(110,300)mL,切口长度6(5,7)cm,淋巴结清扫总数(32.8±14.5)枚,肛门排气时间3(3,4)d,术后住院11(9,12)d。术后发生并发症3例,其中Clavien-DindoⅢ级1例。结论:进展期SiewertⅡ、Ⅲ型食管胃结合部腺癌患者术前新辅助治疗可达到较好的肿瘤降期效果,联合行机器人胃癌根治术是安全、可行的。
Objective:To explore the safety and feasibility of neoadjuvant therapy combined with robotic radical gastrectomy for advanced SiewertⅡandⅢadenocarcinoma of the esophagogastric junction.Methods:The clinical data of 15 patients with advanced Siewert typeⅡandⅢadenocarcinoma of the esophagogastric junction who underwent neoadjuvant therapy combined with robotic radical gastrectomy from Jan.2018 to Nov.2023 were retrospectively analyzed.Results:All the 15 operations were successful,no conversion to laparotomy occurred.Patients received 2-5 cycles of neoadjuvant therapy with an interval of 4(2,5)weeks between the end of treatment and surgery.After neoadjuvant therapy,the tumor remission rate was 73.3%,the operative time was 305(280,367)min,the intraoperative blood loss was 200(110,300)mL,the incision length was 6(5,7)cm,the total number of harvested lymph nodes was(32.8±14.5),the anal exhaust time was 3(3,4)d,and the postoperative hospitalization time was 11(9,12)d.Postoperative complications o ccurred in 3 cases,including one case of Clavien-Dindo gradeⅢ.Conclusions:Preoperative neoadjuvant therapy for advanced Siewert typeⅡandⅢadenocarcinoma of the esophagogastric junction patients can achieve better tumor remission,and combined robotic radical gastrectomy is safe and feasible.
作者
罗子俨
李政焰
杨永璞
陈远丰
宫厚华
杨龙燕
钱锋
余佩武
石彦
LUO Ziyan;LI Zhengyan;YANG Yongpu(Department of General Surgery,the First Affiliated Hospital of AMU,Chongqing 400038,China)
出处
《腹腔镜外科杂志》
2024年第1期6-9,共4页
Journal of Laparoscopic Surgery
基金
重庆市科学技术局技术创新与应用发展专项(CSTB2023TIAD-KPX0053-2)。
关键词
食管胃结合部腺癌
新辅助化疗
胃癌根治术
机器人手术
Adenocarcinoma of the esophagogastric junction
Neoadjuvant chemotherapy
Radical gastrectomy
Robotic surgical procedures
