摘要
目的分析多层螺旋CT(multisliecs spiral CT,MSCT)与磁共振扩散加权成像(diffusionweighted imaging,DWI)对胰腺神经内分泌肿瘤(pancreatic neuroendo crineneoplasms,pNEN)的应用价值。方法对我院2021年7月~2022年11月收治的pN EN患者80例临床资料为观察组,患者均进行MSCT与DWI检测,分析两种检查手段对该病的应用价值。结果对不同病理分级患者MSCT各项检查参数对比显示:肿瘤边缘、形状、囊变坏死、主胰管扩张、远处转移肿瘤最大径以及CT绝对强化的动脉、门脉期值存在明显差异(P<0.05)。经单因素方差分析显示:不同病理分级患者DWI检查的ADC值存在统计学差异,其中G1、G2级患者明显高于G3级,G2级又明显高于G3级(P均<0.05)。将两项检查参数指标纳入Logistic回归模型中得出联合预测数值,随后进行ROC曲线分析显示:将G3患者设定为检测变量,剩余分级患者作为参照变量,联合预测AUC达0.927;预测敏感度92.3%、特异度81.2%。结论MSCT与DWI对pNEN患者的预测诊断均具有一定价值,但为避免单一检测手段的局限性,建议临床中结合其他检查手段进行判定。
Objective To analyze the application value of multislice spiral CT(MSCT)and diffusion weighted imaging(DWI)in the diagnosis of pancreatic neuroendocrine tumors(pNEN).Methods The clinical data of 80 pNEN patients admitted to our hospital from July 2021 to November 2022 were taken as the observation group,and MSCT and DWI tests were performed on all patients.To analyze the application value of two examination methods for this disease.Results A comparison of various MSCT parameters in patients with different pathological grades showed that there were significant differences in tumor margin,shape,cystic necrosis,main pancreatic duct dilation,maximum diameter of distant metastatic tumors,and arterial and portal phase values with absolute CT enhancement(P<0.05).The univariate analysis of variance showed that there were significant differences in the ADC values of DWI examination among patients with different pathological grades,with G1 and G2 patients significantly higher than G3 patients,and G2 patients significantly higher than G3 patients(P all<0.05).Incorporate the two examination parameter indicators into the logistic regression model to obtain a joint prediction value,and then conduct ROC curve analysis.It is shown that with G3 patients as the detection variable and the remaining graded patients as the reference variable,the joint prediction AUC reaches 0.927;The predictive sensitivity was 92.3%and the specificity was 81.2%.Conclusion MSCT and DWI are both valuable in the predictive diagnosis of pNEN patients.However,in order to avoid the limitations of a single detection method,it is recommended to combine other detection methods in clinical diagnosis.
作者
陈丽娟
赵蕾
杜雪菲
CHEN Li-juan;ZHAO Lei;DU Xue-fei(Jianyang City Hospital of Traditional Chinese Medicine,Chengdu 641400,Sichuan Province,China)
出处
《中国CT和MRI杂志》
2024年第2期114-117,共4页
Chinese Journal of CT and MRI
关键词
多层螺旋CT
磁共振扩散加权成像
胰腺神经内分泌肿瘤
应用价值
Multi Slice Spiral CT
Diffusion Weighted Magnetic Resonance Imaging
Neuroendocrine Tumors of The Pancreas
Application Value
