摘要
目的研究多层螺旋CT(MSCT)与MRI对胰腺神经内分泌肿瘤病理分级和肿瘤血供评估的差异性。方法本研究为前瞻性研究,选取我院2019年1月~2022年6月进行诊断并治疗的胰腺神经内分泌肿瘤患者70例作为研究对象,其中G1级患者25例,G2级患者23例,G3级患者22例,富血供胰腺神经内分泌肿瘤患者29例,另选取同期进行健康体检的志愿者70例作为对照组,比较两组、不同肿瘤分级、肿瘤血供的MSCT指标以及MR指标之间的差异,研究MSCT与MRI对胰腺神经内分泌肿瘤病理分级和肿瘤血供评估的诊断意义。结果观察组患者的动脉期以及门脉期的CT绝对强化值低于对照组(P<0.05);观察组患者的动脉期高信号、门脉期高信号低于对照组(P<0.05);不同分级、不同血液供应患者的MSCT动脉期以及门脉期的CT绝对强化值、边缘、形状、囊变坏死、主胰管扩张以及远处转移情况之间的差异有统计学意义(P<0.05);不同分级、不同血液供应患者的MRI动脉期高信号、门脉期高信号、边缘、形状、囊变坏死、主胰管扩张以及远处转移情况之间的差异有统计学意义(P<0.05);MSCT、MRI联合诊断的特异性高于单独检测(P<0.05)。结论MSCT与MRI对胰腺神经内分泌肿瘤病理分级和肿瘤血供评估具有积极的意义。
Objective To investigate the difference between MSCT and MRI in the pathological grading and assessment of tumor blood supply in pancreatic neuroendocrine tumors.Methods In this prospective study,70 patients with pancreatic neuroendocrine tumors diagnosed and treated in our hospital from January 2019 to June 2022 were selected as the research objects,including 25 patients with G1 grade,23 patients with G2 grade,and 22 patients with G3 grade,as well as 29 patients with blood-rich pancreatic neuroendocrine tumors.Another 70 healthy volunteers who underwent physical examination at the same time were selected as the control group.The differences of MSCT and MR indexes between the two groups,patients with different tumor grades,and patients with different tumor blood supply were compared.The diagnostic significance of MSCT and MRI in the pathological grade and assessment of tumor blood supply in pancreatic neuroendocrine tumors were analyzed.Results The CT absolute enhancement values of arterial phase and portal phase in the observation group were significantly lower than those in the control group(P<0.05).The high signal in arterial phase and portal phase in the observation group were significantly lower than those in the control group(P<0.05).There were significant differences in CT absolute enhancement value,margin,shape,cystic degeneration and necrosis,main pancreatic duct dilatation and distant metastasis in arterial phase and portal phase of patients with different grades and blood supplies by MSCT(P<0.05).There were significant differences in high signal in arterial phase and portal phase,margin,shape,cystic necrosis,main pancreatic duct dilatation and distant metastasis in patients with different grades and blood supplies by MRI(P<0.05).The specificity of combination diagnosis of MSCT and MRI was significantly higher than that of single detection(P<0.05).Conclusion MSCT and MRI have positive significance in pathological grading and assessment of tumor blood supply in pancreatic neuroendocrine tumors.
作者
马娜
李义兴
徐一文
侯波
MA Na;LI Yixing;XU Yiwen;HOU Bo(Department of Medical Imaging Radiology,Jianghan Oilfield General Hospital,Qianjiang 433124,China;Department of Nuclear Medicine,Yichang First People's Hospital,Yichang 443000,China;Department of Endocrine,Jianghan Oilfield General Hospital,Qianjiang 433124,China)
出处
《分子影像学杂志》
2023年第1期129-134,共6页
Journal of Molecular Imaging
基金
宜昌市医疗卫生科研项目(A22-2-039)。
