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成人退行性脊柱侧凸的预后因素分析及基于脊柱矢状面平衡的矫形策略探讨 被引量:1

Evaluation of prognostic factors for adult degenerative scoliosis and exploration of corrective strategies based on spinal sagittal balance
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摘要 目的分析影响成人退行性脊柱侧凸(ADS)患者术后2年功能性预后的危险因素,并探讨基于脊柱矢状面平衡的手术策略。方法纳入2018年5月—2020年5月应急总医院采用后路融合内固定术矫形的ADS患者79例,记录其年龄、性别、体质量指数(BMI)等一般资料,采集患者术前及术后2年的Oswestry功能障碍指数(ODI)、脊柱侧凸研究学会22项患者问卷(SRS-22)评分、腰背部和下肢疼痛视觉模拟量表(VAS)评分,测量术前及术后2年的骨盆倾斜角(PT)、骨盆投射角(PI)、腰椎前凸角(LL)、矢状面垂直偏距(SVA)、冠状面平衡、T1骨盆角(T1PA)及PI-LL,记录并统计术后并发症发生情况。根据术后2年ODI将患者分为功能最佳组(ODI≤15%)和功能最差组(ODI>50%),比较2组患者各指标的差异,采用多因素logistic回归分析评价术后功能的影响因素。结果79例患者总体并发症发生率为41.8%(33/79),术后2年ODI、SRS-22评分、腰背部疼痛VAS评分较术前改善,差异均有统计学意义(P<0.05)。术后2年功能最差组21例,功能最佳组30例。功能最差组患者BMI、术后重症并发症发生率高于功能最佳组;术前ODI、SRS-22评分差于功能最佳组,术前矢状面失衡(SVA≥5 cm)患者比例高于功能最佳组;术后2年ODI、SRS-22评分、腰背部和下肢痛VAS评分差于功能最佳组,矢状面失衡患者比例、PI-LL和T1PA高于功能最佳组;差异均有统计学意义(P<0.05)。多因素logistic回归分析结果显示,高BMI、术前高ODI、术后2年SVA≥5 cm和术后2年高T1PA是预后不良的危险因素。结论手术矫形能够改善ADS患者的功能和生活质量,BMI、术前ODI、术后2年SVA和术后2年T1PA影响术后功能恢复,故应基于脊柱矢状面整体平衡状态制订ADS手术策略。 Objective To explore the risk factors associated with functional outcome at 2 years after surgery in adult degenerative scoliosis(ADS)patients,and discuss the surgical strategy based on the spinal sagital balance.Methods A total of 79 ADS patients who underwent posterior fusion internal fixation surgery at the Emergency General Hospital from May 2018 to May 2020 were included.The general information such as age,gender,body mass index(BMI)were recorded.The Oswestry disability index(ODI),Scoliosis Research Society-22 patient questionnaire(SRS-22)score,low back and leg pain visual analogue scale(VAS)scores,the pelvic tilt(PT),pelvic incidence(PI),lumbar lordosis(LL),sagittal vertical axis(SVA),coronal balance,T pelvic angle(TPA)and PI-LL at pre-operation and postoperative 2 years were recorded.The incidence of postoperative complications were recorded.According to the ODI at postoperative 2 years,patients were divided into the best function group(ODI≤15%)and the worst function group(ODI>50%).The differences in various indicators between the 2 groups were compared,and the influencing factors of postoperative function were evaluated using multivariate logistic regression analysis.Results The overall incidence of complications in 79 patients was 41.8%(33/79),and the ODI,SRS-22 score and low back pain VAS score at postoperative 2 years were all improved compared to the pre-operation,with a statistical significance(P<0.05).At postoperative 2 years,there were 21 cases in the worst function group and 30 cases in the best function group.In the worst function group the BMI and incidence of severe postoperative complications were higher than those in the best function group;the preoperative ODI and SRS-22 score were lower than those in the best function group,and the proportion of patients with sagittal imbalance(SVA≥5 cm)at pre-operation was higher than that in the best function group;the ODI,SRS-22 score,low back and leg pain VAS scores at postoperative 2 years were worse than those in the best function group;the propor
作者 杜传超 海宝 刘宇 商玉臣 何保华 石航 朱伟 高延征 李危石 刘晓光 Du Chuanchao;Hai Bao;Liu Yu;Shang Yuchen;He Baohua;Shi Hang;Zhu Wei;Gao Yanzheng;Li Weishi;Liu Xiaoguang(Second Department of Orthopaedics,Emergency General Hospital,Beijing 100028,China;Department of Orthopaedics,Peking University Third Hospital,Beijing 100191,China;Department of Spinal and Spinal Cord Surgery,Henan Provincial Peoples Hospital,Zhengzhou 463599,Henan,China)
出处 《脊柱外科杂志》 2024年第1期5-11,共7页 Journal of Spinal Surgery
基金 国家重点研发计划(2019YFB2204905)。
关键词 胸椎 腰椎 脊柱侧凸 矫形外科手术 预后 Thoracic vertebrae Lumbar vertebrae Scoliosis Orthopaedic procedures Prognosis
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