摘要
目的:分析急性心肌梗死(AMI)患者经皮冠状动脉介入(PCI)术后再发的相关危险因素。方法:选取98例接受PCI术的AMI患者,采用一般资料问卷、8项Morisky服药依从性量表(MMAS-8),调查术后再发情况,比较再发患者与未再发者年龄、性别、吸烟史、饮酒史、合并基础疾病、术前Killip分级、栓塞血管分类、术后TIMI血流、病变支数、服药依从性、支架来源等项目。使用Logistic回归分析AMI患者PCI术后再发相关危险因素。结果:AMI患者PCI术后再发率为16.33%;单因素分析结果显示,年龄、吸烟史、合并糖尿病、术前killip分级、病变支数与AMI患者PCI术后再发相关(P<0.05);多因素分析结果显示,年龄≥60岁(β=1.235,OR=3.438,95%CI=1.092~10.818)、合并糖尿病(β=1.199,OR=3.316,95%CI=1.097~10.022)、吸烟史(β=1.168,OR=3.214,95%CI=1.059~9.756)、术前Killip分级Ⅱ-Ⅳ级(β=1.515,OR=4.550,95%CI=1.206~17.169)、多支病变(β=1.383, OR=3.986,95%CI=1.315~12.081)是AMI患者PCI术后再发的高危因素(P<0.05)。结论:AMI患者PCI术后再发与年龄、合并糖尿病、吸烟史、术前killip分级、病变支数有关。
Objective:To analyze the relevant risk factors for readmission after percutaneous coronary intervention(PCI)in patients with acute myocardial infarction(AMI).Methods:98 AMI patients who underwent PCI were selected and investigated for postoperative recurrence using a general information questionnaire and an 8-item Morisky medication adherence scale(MMAS-8).The age,gender,smoking history,drinking history,comorbidities,preoperative Killip grading,classification of embolic vessels,postoperative TIMI blood flow,number of lesion branches,medication adherence,and stent source were compared between recurrent and non-recurrent patients.Logistic regression was used to analyze the risk factors for recurrence after PCI in AMI patients.Results:The readmission rate of AMI patients after PCI was 16.33%;univariate analysis showed that age,smoking history,diabetes,preoperative killip grade,number of diseased branches were related to the readmission of AMI patients after PCI(P<0.05);patients with concomitant hyperlipidemia,hypertension,gender,per capita monthly income,history of alcohol consumption,classification of thrombotic vessels,marital status,educational level,medication compliance,postoperative TIMI blood flow,and stent source were not associated with readmission after PCI in AMI patients(P>0.05).Multivariate analysis showed that age over 60 years old(β=1.235,OR=3.438,95%CI=1.092~10.818),combined with diabetes(β=1.199,OR=3.316,95%CI=1.097~10.022)smoking history(β=1.168,OR=3.214,95%CI=1.059~9.756),preoperative kill grade II-IV(β=1.515,OR=4.550,95%CI=1.206~17.169),multiple vessel lesions(β=1.383,OR=3.986,95%CI=1.315~12.081)were high-risk factors for readmission after PCI in AMI patients(P<0.05).Conclusion:The readmission of AMI patients after PCI is related to age,diabetes,smoking history,preoperative Killip grade and number of diseased branches.
作者
黄菁
姚娟
朱宁
匡林华
HUANG Jing;YAO Juan;ZHU Ning;KUANG Linhua(Ji′an Central People′s Hospital,Ji′an 343000,China)
出处
《华夏医学》
CAS
2023年第6期38-43,共6页
Acta Medicinae Sinica
基金
江西省卫生健康委员会科技计划项目(202212825)。
关键词
急性心肌梗死
经皮冠状动脉介入
再发
危险因素
acute myocardial infarction
percutaneous coronary intervention
recurrent
risk factors