摘要
目的探讨分析老年胃溃疡出血患者再发出血的相关危险因素。方法选取2020年3月至2022年3月许昌市中心医院收治的140例老年胃溃疡出血患者作为研究对象,收集患者性别、年龄、发病部位、胃溃疡长径、出血活动度、是否为胃溃疡A1期、是否合并幽门螺杆菌(Hp)感染、有无吸烟史、有无饮酒史、合并其他慢性疾病种类(≤2种、>2种)、是否进行消化内镜治疗、是否长期使用非甾体抗炎药(NSAIDs)等资料,并根据患者止血成功后1个月内是否再发出血将患者分为发生组与未发生组。多因素Logistic回归分析老年胃溃疡出血患者再发出血的危险因素。结果140例老年胃溃疡出血患者均于止血成功后随访1个月,随访过程中21例(150%)患者再发出血,设为发生组;119例(850%)患者未再发出血,设为未发生组。单因素分析结果显示,发生组胃溃疡A1期、Hp感染、未进行消化内镜治疗、长期使用NSAIDs的患者比例均明显高于未发生组(χ^(2)=4269、7381、7580、11836,P=0039、0007、0006、0001);多因素Logistic回归分析结果显示,胃溃疡A1期、Hp感染、未进行消化内镜治疗、长期使用NSAIDs是老年胃溃疡出血患者再发出血的独立危险因素(95%CI为1039~9660、1909~58707、0059~0585、1880~18559,P=0043、0007、0004、0002)。结论胃溃疡A1期、Hp感染、未进行消化内镜治疗、长期使用NSAIDs是老年胃溃疡出血患者再发出血的独立危险因素,临床应根据患者具体情况制定针对性干预措施,以降低再出血发生风险。
Objective To study risk factors for rebleeding of gastric ulcer hemorrhage in the elderly patients.Methods 140 elderly patients with gastric ulcer hemorrhage,admitted to Xuchang Central Hospital from March 2020 to March 2022,were selected as research subjects,and the following data of patients were collected,including sex,age,site of ulcer,gastric ulcer long diameter,bleeding activity,stage A1 gastric ulcer,Helicobacter pylori(Hp)infection,history of smoking and drinking,number of other types of chronic diseases(≤2 types,>2 types),digestive endoscopic treatment,and long-term use of nonsteroidal anti-inflammatory drugs(NSAIDs).These patients were divided into the occurrence group and non-occurrence group based on whether rebleeding occurred within one month after successful hemostasis.Multivariate Logistic regression analysis was conducted to identify the risk factors for rebleeding of gastric ulcer bleeding in the elderly patients.Results All the 140 elderly patients with gastric ulcer hemorrhage were followed up for one month after hemosta-sis.During the follow-up,21 patients(150%)who experienced rebleeding were set as the occurrence group,while 119 patients(850%)who did not suffer rebleeding were set as the non-occurrence group.Results of the univariate analysis showed that patients with stage A1 gastric ulcers,Hp infection,free of digestive endoscopic treatment,and long-term use of NSAIDs had notably higher proportions in the occurrence group compared with the non-occurrence group(χ^(2)=4269,7381,7580 and 11836,P=0039,0007,0006 and 0001).The multivariate Logistic regression analysis found that stage A1 gastric ulcer,Hp infection,free of digestive endoscopic treatment,and long-term use of NSAIDs were independent risk factors for rebleeding of gastric ulcer hemorrhage in the elderly patients(95%CI:1039-9660,1909-58707,0059-0585 and 1880-18559,P=0043,0007,0004 and 0002).Conclusion Stage A1 gastric ulcer,Hp infec-tion,free of digestive endoscopic treatment,and long-term use of NSAIDs are independent risk factor
作者
卞卡
张巍巍
BIAN Ka;ZHANG Weiwei(Department of Gastroenterology,Xuchang Central Hospital,Xuchang,Henan 461000,China;Department of Gastrointestinal Surgery,Xuchang Central Hospital,Xuchang,Henan 461000,China)
出处
《中国烧伤创疡杂志》
2024年第1期62-65,共4页
The Chinese Journal of Burns Wounds & Surface Ulcers
关键词
胃溃疡出血
老年
再出血
消化内镜治疗
幽门螺杆菌
非甾体抗炎药
危险因素
Gastric ulcer hemorrhage
Elderly
Rebleeding
Digestive endoscopic treatment
Helicobacter pylori
Nonsteroidal anti-inflammatory drugs
Risk factors