摘要
目的观察胎儿颅脑正中矢状位MRI脑桥生物学指标与孕周的相关性。方法回顾性分析226胎孕23~38周中枢神经系统未见明显异常胎儿(正常组)及17胎异常胎儿(异常组)头部MRI,基于正中矢状位图像获得脑桥生物学指标,包括脑桥前后径(PAD)、脑桥截面积(TPA)、脑桥基底部前后径(AP)、脑桥基底部上下径(CC)、脑桥基底部截面积(BPA)及中脑脑桥角(MAP)。根据孕周将正常组胎儿分为8个亚组,统计不同孕周胎儿脑桥生物学指标分布范围,分析正常组胎儿脑桥生物学指标与孕周的相关性,并据以判断异常组胎儿脑桥发育。结果正常组胎儿PAD、TPA、AP、CC及BPA均与孕周均呈线性正相关(r=0.887、0.914、0.787、0.866、0.865,P均<0.001),MAP与孕周无明显相关(P>0.05)。异常组17胎中,8胎PAD异常、8胎TPA异常、14胎AP异常、3胎CC异常、11胎BPA异常。结论胎儿颅脑正中矢状位MRI脑桥生物学指标(PAD、TPA、AP、CC、BPA)与孕周呈正相关,可用于评估胎儿脑桥发育。
Objective To observe the correlations of pontine biological indicators on fetal brain median sagittal MRI with gestational week.Methods Data of head MRI of 226 normal fetuses without obvious abnormalities of central nervous system(normal group)and 17 fetuses with abnormalities(abnormal group)at gestational age of 23 to 38 weeks were retrospectively analyzed.Pontine biological indicators based on median sagittal MRI were obtained,including pons anteroposterior diameter(PAD),total pons area(TPA),pontine basal anteroposterior length(AP),pontine basal cranio-caudal length(CC),basis pontis area(BPA)and pontine angle of midbrain(MAP).According to the gestational week,the fetuses of normal group were divided into 8 subgroups.The distributing ranges of pontine biological indicators at different gestational weeks were analyzed,and the correlations of pontine biological indicators with gestational week in normal group were explored,and the developmental status of fetal pons in abnormal group were assessed.Results In normal group,PAD,TPA,AP,CC and BPA all showed linear positive correlation(r=0.887,0.914,0.787,0.866,0.865,all P<0.001),while MAP was not significantly correlated with gestational week(P>0.05).Among 17 fetuses in abnormal group,abnormal PAD or TPA was found each in 8 fetuses,abnormal AP was observed in 14,abnormal CC was noticed in 3 and abnormal BPA was found in 11 fetuses.Conclusion Fetal pontine biological indicators such as PAD,TPA,AP,CC and BPA on median sagittal MRI were positively correlated with gestational week,hence being able to be used for evaluating fetal pontine development.
作者
侯伶秀
刘炳光
袁鹰
廖伊梅
朱巧珍
郭洪波
谭莹
温慧莹
严芳
李胜利
HOU Lingxiu;LIU Bingguang;YUAN Ying;LIAO Yimei;ZHU Qiaozhen;GUO Hongbo;TAN Ying;WEN Huiying;YAN Fang;LI Shengli(The First School of Clinical Medicine,Southern Medical University,Guangzhou 510515,China;Department of Ultrasound,Shenzhen Maternity and Child Healthcare Hospital,Shenzhen 518028,China;Department of Ultrasound,Guilin Medical College Affiliated Hospital,Guilin 541001,China;Department of Radiology,Shenzhen Maternity and Child Healthcare Hospital,Shenzhen 518028,China;Department of Ultrasound,Heyuan People's Hospital,Heyuan 517000,China;Institute of Maternal and Child Medicine,Shenzhen Maternity and Child Healthcare Hospital,Shenzhen 518028,China)
出处
《中国医学影像技术》
CSCD
北大核心
2024年第1期88-92,共5页
Chinese Journal of Medical Imaging Technology
关键词
胎儿
脑桥
磁共振成像
fetus
pons
magnetic resonance imaging
