摘要
目的 分析急性乙醇中毒合并上消化道出血治疗效果。方法 回顾性选取2021年3月—2023年3月北京市平谷区医院急诊科治疗的急性乙醇中毒合并上消化道出血患者98例的临床资料。按不同治疗方式分为两组,每组49例,对照组接受基础治疗,研究组在对照组基础上接受奥曲肽、奥美拉唑联合醒脑静治疗,比较两组血清神经递质水平、临床疗效、完全清醒时间、意识初步恢复时间、住院时间、止血时间、尿量恢复时间、红细胞输注量、大便隐血转阴时间、血常规指标。结果 研究组患者血清神经递质水平低于对照组,差异有统计学意义(P<0.05)。研究组治疗总有效率为97.95%,高于对照组的83.68%,差异有统计学意义(χ~2=5.995,P=0.014)。研究组完全清醒时间、意识初步恢复时间、住院时间、止血时间均短于对照组,差异有统计学意义(P<0.05)。研究组尿量恢复时间、红细胞输注量、大便隐血转阴时间优于对照组,差异有统计学意义(P<0.05)。研究组血细胞比容、血红蛋白、红细胞比容水平高于对照组,尿素氮水平低于对照组,差异有统计学意义(P<0.05)。结论 对急性乙醇中毒合并上消化道出血患者实施奥曲肽、奥美拉唑联合醒脑静治疗可有效改善患者血清神经递质水平,提高临床疗效,进而缩短患者住院时间。
Objective To analyze the treatment effect of acute alcohol poisoning combined with upper gastrointestinal bleeding.Methods The clinical data of 98 patients with acute alcohol poisoning combined with upper gastrointestinal bleeding treated in the Department of Emergency Medicine of Beijing Pinggu District Hospital from March 2021 to March 2023 were retrospectively selected and were divided into two groups according to different treatment modalities,with 49 cases in each group.The control group received basic treatment,and the study group received octreotide and omeprazole combined with Xingnaojing treatment on the basis of the control group.Compared the serum neurotransmitter level,clinical efficacy,time of complete wakefulness,time of initial recovery of consciousness,hospitalization time,time of hemostasis,time of recovery of urinary output,volume of red blood cell transfusion,time of conversion of fecal occult blood to negative,and blood routine indexes of the two groups.Results The serum neurotransmitter level of patients in the study group was lower than that of the control group,and the difference was statistically significant (P<0.05).The total effective rate of treatment in the study group was 97.95%,which was higher 83.68%in the control group,and the difference was statistically significant (χ~2=5.995,P=0.014).The time of complete wakefulness,time of initial recovery of consciousness,hospitalization time,and hemostasis time of the study group were shorter than those of the control group,and the difference was statistically significant (P<0.05).The time for recovery of urine output,red blood cell transfusion,and fecal occult blood conversion in the study group was better than those in the control group,and the difference was statistically significant (P<0.05).The levels of hematocrit,hemoglobin,and erythrocyte pressure volume in the study group were higher than those in the control group,and the level of urea nitrogen was lower than that in the control group,and the difference was statistically significan
作者
王亚男
刘自新
WANG Yanan;LIU Zixin(Department of Emergency Medicine,Beijing Pinggu District Hospital,Beijing,101200 China)
出处
《中外医疗》
2023年第32期1-4,18,共5页
China & Foreign Medical Treatment
关键词
急性乙醇中毒
上消化道出血
急诊治疗方法
临床疗效
Acute alcohol poisoning
Upper gastrointestinal bleeding
Emergency treatment
Clinical efficacy
