摘要
目的探讨低钠血症对老年新型冠状病毒感染患者预后的影响。方法回顾性分析2022年12月—2023年2月山东第一医科大学附属省立医院收治的151例新型冠状病毒感染患者的临床资料。根据患者入院时血钠水平分为低钠血症、正常血钠者,用Kaplan-Meier进行生存分析,采用Log-rank检验比较两者生存情况。比较不同临床特征老年新型冠状病毒感染患者预后。采用多因素logistic回归分析低钠血症对老年新型冠状病毒感染患者预后影响。结果151例老年新型冠状病毒感染患者中,低钠血症56例、血钠正常95例。Kaplan-Meier生存分析结果显示,低钠血症者总体生存低于血钠正常者(P=0.006)。多因素logistic回归分析结果显示,低钠血症(OR=4.902,95%CI:1.453~16.537,P=0.010)是老年新型冠状病毒感染患者预后的影响因素。结论老年新型冠状病毒感染患者并发低钠血症影响患者生存情况。
Objective To investigate the effect of hyponatremia on prognosis of elderly patients with COVID-19 infection.Methods The clinical data of 151 patients with COVID-19 infection admitted to Shandong Provincial Hospital Affiliated to Shandong First Medical University from December 2022 to February 2023 were retrospectively analyzed.Patients were divided into hyponatremia and normal natremia according to the blood sodium level at admission.Kaplan-Meier survival analysis was performed,and Log-rank test was used to compare the survival of the two groups.To compare the prognosis of elderly patients with COVID-19 infection with different clinical characteristics.Multivariate logistic regression was used to analyze the effect of hyponatremia on prognosis of elderly patients with COVID-19 infection.Results Among 151 elderly patients infected with COVID-19,56 cases were hyponatremia and 95 cases were normal natremia.KaplanMeier survival analysis showed that the overall survival of patients with hyponatremia was lower than that of those with normal natremia(P=0.006).Multivariate logistic regression analysis showed that hyponatremia(OR=4.902,95%CI:1.453-16.537,P=0.010)was a prognostic factor in elderly patients with COVID-19 infection.Conclusion The survival of elderly patients with COVID-19 infection complicated with hyponatremia is affected.
作者
朱彤
姜曼
ZHU Tong;JIANG Man(School of Nursing and Rehabilitation,Shandong University,Jinan 250012,China;Department of Geriatrics,Shandong Provincial Hospital Affiliated to Shandong First Medical University,Jinan 250012,China)
出处
《老年医学研究》
2023年第6期19-22,共4页
Geriatrics Research
