摘要
目的探讨超声引导下腰脊神经脉冲射频治疗下肢急性带状疱疹疼痛的临床疗效。方法选取2019年12月至2021年11月广丰区人民医院收治的60例下肢急性带状疱疹疼痛患者作为研究对象,按照随机信封法分为A组、B组与C组,每组20例。A组采用常规药物治疗,B组于超声引导下行神经阻滞治疗,C组于超声引导下行腰脊神经脉冲射频治疗,比较3组血清S100β蛋白、神经元特异性烯醇化酶(NSE)、超敏C反应蛋白(hs-CRP)水平和并发症发生情况及不同时间视觉模拟评分法(VAS)评分。结果3组S100β、NSE、hs-CRP水平比较差异有统计学意义(P<0.05);B组、C组血清S100β、NSE、hs-CRP水平均低于A组,且C组低于B组,差异有统计学意义(P<0.05)。3组并发症发生率比较差异有统计学意义(P<0.05);C组并发症发生率低于A组,差异有统计学意义(P<0.05);其他组间两两比较差异均无统计学意义。治疗前,3组VAS评分比较差异无统计学意义;治疗1、7 d,3组VAS评分比较差异有统计学意义(P<0.05);治疗7 d,B组、C组VAS评分均低于A组,且C组低于B组,差异有统计学意义(P<0.05);治疗1 d,C组VAS评分低于A组,差异有统计学意义(P<0.05);其他两组间比较差异无统计学意义。结论超声引导下腰脊神经脉冲射频治疗下肢急性带状疱疹疼痛疗效显著,可有效改善患者S100β、NSE、hs-CRP水平,降低其疼痛程度,安全性高,值得临床应用推广。
Objective To investigate the clinical efficacy of ultrasound-guided lumbar spinal nerve pulsed radiofrequency in the treatment of acute herpes zoster pain in the lower limbs.Methods 60 patients with acute herpes zoster pain in the lower limbs admitted to Guangfeng District People's Hospital from December 2019 to November 2021 were selected as the study subjects,and they were divided into the group A,the group B and the group C according to the envelope randomized grouping method,with 20 cases in each group.The group A received conventional drug treatment,the group B received ultrasound-guided descending nerve block therapy,and group C received ultrasound-guided lumbar spinal nerve pulsed radiofrequency,the levels of serum S100βprotein,neuron-specific enolase(NSE),hypersensitive C-reactive protein(hs-CRP),complications and VAS scores at different times were compared among the three groups.Results There were significant differences in S100β,NSE and hs-CRP levels among the three groups(P<0.05);the levels of S100β,NSE and hs-CRP in the group B and group C were lower than those in the group A,and the group C was lower than the group B,and the differences were statistically significant(P<0.05).There was significant difference in the incidence of complications among the three groups(P<0.05);the incidence of complications in the group C was lower than that in the group A,the difference was statistically significant(P<0.05);there was no significant difference between other groups.Before treatment,there was no significant difference in VAS score among the three groups;at 1 and 7 days after treatment,the VAS scores of the three groups were significantly different(P<0.05);at 7 d after treatment,the VAS scores in the group B and group C were lower than those in the group A,and group C was lower than group B,the differences were statistically significant(P<0.05);at 1 d after treatment,the VAS score in the group C was lower than that in the group A,and the difference was statistically significant(P<0.05),there was no signifi
作者
喻洋
王小玲
邓利旺
黄俊
徐翘
YU Yang;WANG Xiaoling;DENG Liwang;HUANG Ju;XU Qiao(The Second Department of Pain and Osteology,Guangfeng District People's Hospital,Shangrao,Jiangxi,334600,China;Department of Nursing,Guangfeng District People's Hospital,Shangrao,Jiangxi,334600,China;Department of Pain,Hengfeng County People's Hospital,Shangrao,Jiangxi,334399,China;Department of Rehabilitation Medicine,Guangfeng District People's Hospital,Shangrao,Jiangxi,334600,China)
出处
《当代医学》
2023年第15期44-47,共4页
Contemporary Medicine
基金
江西省卫生健康委科技计划项目(20205015)。
关键词
超声引导
下肢急性带状疱疹疼痛
腰脊神经脉冲射频
并发症
Ultrasound-guided
Acute herpes zoster pain in the lower limbs
Lumbar spinal nerve pulsed radiofrequency
Complication
