摘要
目的:观察增强型体外反搏(EECP)在经皮冠状动脉介入(PCI)术后再发心绞痛患者中的应用效果。方法:选取2020年3月至2023年3月该院收治的72例PCI术后再发心绞痛患者进行前瞻性研究,按照随机数字表法将其分为对照组和观察各36例。对照组采用常规药物治疗,观察组在对照组基础上采用EECP治疗。比较两组临床疗效,治疗前后心绞痛发作频率、心绞痛持续时间、心功能[6 min步行试验(6MWT)]水平、血管内皮功能指标[一氧化氮(NO)、内皮素-1(ET-1)、血管内皮生长因子(VEGF)]水平及不良反应发生率。结果:观察组治疗总有效率为94.44%,高于对照组的77.78%,差异有统计学意义(P<0.05);治疗后,两组心绞痛发作频率、心绞痛持续时间均少于治疗前,且观察组少于对照组,两组6MWT距离均长于治疗前,且观察组长于对照组,差异有统计学意义(P<0.05);治疗后,两组NO、VEGF水平均高于治疗前,且观察组高于对照组,两组ET-1水平低于治疗前,且观察组低于对照组,差异有统计学意义(P<0.05);两组均未出现明显不良反应。结论:EECP应用于PCI术后再发心绞痛患者,可提高临床疗效,减少心绞痛发作频率和心绞痛持续时间,改善心功能和血管内皮功能,效果优于单纯常规治疗。
Objective:To observe application effects of enhanced external counterpulsation(EECP)in patients with recurrent angina pectoris after percutaneous coronary intervention(PCI).Methods:A prospective study was conducted on 72 patients with recurrent angina pectoris after PCI admitted to the hospital from March 2020 to March 2023.According to the random number table method,they were divided into control group and observation group,36 cases in each group.The control group was treated with conventional drugs,while the observation group was treated with EECP on the basis of that of the control group.The clinical efficacy,the frequency of angina pectoris,the duration of angina pectoris,the cardiac function[6 min walking test(6 MWT)]level,the vascular endothelial function index levels[nitric oxide(NO),endothelin-1(ET-1),vascular endothelial growth factor(VEGF)],and the incidence of adverse reactions were compared between the two groups before and after the treatment.Results:The total effective rate of treatment in the observation group was 94.44%,which was higher than 77.78%in the control group,and the difference was statistically significant(P<0.05).After the treatment,the frequency and duration of angina pectoris in the two groups were less than those before the treatment,and those in the observation group were less than those in the control group;the 6MWT distance levels of the two groups were longer than those before the treatment,and the that in observation group was longer than that in the control group;and the differences were statistically significant(P<0.05).After the treatment,the levels of NO and VEGF in the two groups were higher than those before the treatment,and those in the observation group were higher than those in the control group;the ET-1 levels were lower than those before the treatment,and that in the observation group was lower than that in the control group;and the differences were statistically significant(P<0.05).However,there were no serious adverse reactions in both groups.Conclusions:The applic
作者
聂亮
NIE Liang(3^(rd)Ward of Department of Cardiology of the People No.3 Hospital of Anyang,Anyang 455000 Henan,China)
出处
《中国民康医学》
2023年第22期24-26,30,共4页
Medical Journal of Chinese People’s Health
关键词
增强型体外反搏
经皮冠状动脉介入术
心绞痛
血管内皮功能
心功能
不良反应
Enhanced external counterpulsation
Percutaneous coronary intervention
Angina pectoris
Vascular endothelial function
Cardiac function
Adverse reaction
