摘要
宫颈癌是女性下生殖道最常见恶性肿瘤,目前公认,高危型人乳头瘤病毒(HR-HPV)持续感染是导致该病发病的主要原因。对于防治宫颈癌前病变及预防宫颈癌,探究HR-HPV持续感染的发生机制至关重要。有研究显示,HR-HPV的感染与阴道微生态环境,如阴道微生物、阴道局部免疫系统等具有相关性。文章探讨阴道微生态环境与HR-HPV感染的相关性,旨在寻找防治HR-HPV持续感染的新思路,为进一步探索宫颈癌治疗提供理论依据。
Cervical cancer is the most common malignant tumor of female lower reproductive tract.At present,it is recognized that the continuous infection of high-risk human papillomavirus(HR-HPV)is the main cause of its incidence.For the prevention and treatment of cervical precancerous lesions and the prevention of cervical cancer,it is important to explore the mechanism of persistent infection of HR-HPV.Studies have shown that HR-HPV infection is related to vaginal micro ecological environment,such as vaginal microorganisms and vaginal local immune system.This paper deeply explores the correlation between vaginal micro ecological environment and HR-HPV infection,in order to find new ideas for the prevention and treatment of HR-HPV persistent infection,and provide a theoretical basis for further exploring the treatment of cervical cancer.
作者
门佳囡
王震
王丹凝(综述)
丛慧芳(审校)
Men Jianan;Wang Zhen;Wang Danning;Cong Huifang(Heilongjiang University of Tradtional Chinese Medicine,Heilongjiang Province,Harbin 150040,China)
出处
《疑难病杂志》
CAS
2023年第12期1332-1335,共4页
Chinese Journal of Difficult and Complicated Cases
基金
黑龙江省自然科学基金面上项目(051514)
黑龙江省中医药科研项目(2H716-028)
黑龙江省卫生计生委科研课题(2016-552)
关键词
阴道微生态环境
阴道微生物
高危型人乳头瘤病毒
宫颈癌
Vaginal micro ecological environment
Vaginal microorganism
High-risk human papillomavirus
Cervical carcinoma
