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妇科门诊不同阴道症状就诊者阴道微生态状况调查 被引量:53

Microecological investigation of vaginal microflora in women with varying degree gynecologic symptoms in clinics
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摘要 目的了解妇科门诊因不同阴道症状而就诊的女性阴道微生态状况。方法2006年3月至2007年10月,选择在北京大学第一医院妇科门诊因外阴瘙痒、阴道分泌物增多、阴道分泌物有异味等症状就诊的6982例女性,取其阴道分泌物,进行pH值、H,O,含量检测,并经革兰染色后在油镜下观察,进行阴道微生态(阴道菌群的密集度、多样性、优势菌、炎性反应状况等)状况评价。结果6982例就诊者中,阴道微生态正常750例,占10.74%(750/6982);阴道微生态失调6232例,占89.26%(6232/6982);后者包括细菌性阴道病(BV)患者729例,占10.44%(729/6982);外阴阴道假丝酵母菌病(VVC)患者1527例,占21.87%(1527/6982);BV合并VVC95例,占1.36%(95/6982);菌群异常1229例,占17.60%(1229/6982);菌群正常但阴道pH值、清洁度、乳杆菌功能异常2652例,占37.98%(2652/6982)。结论妇科门诊不同阴道症状就诊者阴道微生态可表现为正常状态,也可表现为失调状态;阴道微生态评价能够指导临床医师全面评价阴道微生态状况。 Objective To investigate the microecological status of vaginal microflora in the women with different vaginal symptoms. Methods From March 2006 to October 2007, 6982 cases with varying degree vaginal symptoms including pruritus, increaseed leucorrhea, the leucorrhea having unusual smell, in the gynecology outpatient department were studied. The vagina secretions were examined in terms of the pH value, the hydrogen peroxide test, and Gram dyeing inspection of vaginal bacteria and microecology appraisal for colony's density, the multiplicity, the superiority fungus, and the inflammatory response. Results Among 6982 patients, normal vaginal microecology was identified in 750 ( 10. 74%, 750/6982 ) ; abnormal microecology was found in 6232 (89.26%, 6232/6982 ); bacterial vaginosis (BV) was detected in 729( 10. 44% , 729/6982) ; vulvovaginal candidiasis ( VVC ) was in 1527 ( 21.87% , 1527/6982 ). Ninety five patients (1.36% ,95/6982) were with both BV and VVC. Abnormal bacteria colonies were found in 1229(17.60% ,1229/6982),and others were found in 2652(37.98% ,2652/6982). Conclusions The vaginal microecology in the women with different vaginal symptoms can be either normal or abnormal. Microecology clinical evaluation system can assess the vaginal microecosystem.
出处 《中华妇产科杂志》 CAS CSCD 北大核心 2009年第1期6-8,共3页 Chinese Journal of Obstetrics and Gynecology
关键词 阴道病 细菌性 念珠菌病 外阴阴道 抗生作用 评价研究 Vaginosis, bacterial Candidiasis, vulvovaginal Antibiosis Evaluation studies
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