摘要
目的:观察艾灸联合西药治疗输尿管镜碎石术(URL)后输尿管支架管综合征(USS)的临床疗效。方法:将150例URL术后置入输尿管支架管的上尿路结石患者随机分为艾灸组(50例,脱落1例)、安慰艾灸组(50例,脱落3例)和空白对照组(50例)。空白对照组不行任何干预。在口服盐酸坦索罗辛缓释胶囊(术后第1天开始,每次0.2 mg,每日1次,连续治疗4周)基础上,艾灸组艾灸关元、双侧肾俞,安慰艾灸组采用假艾灸相同穴位,均每次15 min,每日1次,每周6次,共治疗4周。比较各组患者治疗前及治疗1、2、4周后下尿路症状、身体疼痛情况、一般情况、工作能力、性生活满意度评分,比较各组治疗4周后结石清除率及尿路感染、口服止痛药情况。结果:各组治疗1周后下尿路症状、身体疼痛情况、一般情况评分及治疗2、4周后下尿路症状、身体疼痛情况、一般情况、工作能力评分均较治疗前降低(P<0.01)。艾灸组治疗1、2、4周后下尿路症状、身体疼痛情况评分低于空白对照组及安慰艾灸组(P<0.01,P<0.05)。艾灸组治疗1周后一般情况评分低于空白对照组(P<0.01),治疗2、4周后低于空白对照组及安慰艾灸组(P<0.01,P<0.05)。艾灸组治疗1、2周后工作能力评分低于空白对照组(P<0.05,P<0.01),治疗4周后低于空白对照组及安慰艾灸组(P<0.01,P<0.05)。艾灸组结石清除率为95.9%(47/49),高于空白对照组的80.0%(40/50,P<0.05)。艾灸组(28.6%,14/49)和安慰艾灸组(40.4%,19/47)口服止痛药比例低于空白对照组(76.0%,38/50,P<0.01)。结论:艾灸联合西药可缓解URL术后患者下尿路症状及身体疼痛,加快一般情况及工作能力恢复。
Objective To observe the clinical efficacy of moxibustion combined with western medication on ureteral stent-related symptoms after ureteroscopic lithotripsy(URL).Methods One hundred and fifty patients with upper urinary tract calculus implanted with ureteral stents after URL were randomly divided into a moxibustion group(50 cases,1 case dropped out),a placebo moxibustion group(50 cases,3 cases dropped out)and a blank control group(50 cases).No intervention was performed in the blank control group.On the basis of oral administration with tamsulosin hydrochloride sustained release capsule(starting from the first day after surgery,once a day,0.2 mg each time,continuously for 4 weeks),in the moxibustion group,moxibustion was operated at Guanyuan(CV 4)and bilateral Shenshu(BL 23);the sham-moxibustion was delivered at the same acupoints in the placebo moxibustion group,once daily,6 times a week,for 15 min in each treatment.The duration of treatment was 4 weeks.Before treatment,and after 1,2 and 4 weeks of treatment,the scores of lower urinary tract symptoms,body pain,general health,work performance and satisfaction of sexual matters were compared among the 3 groups.The tract calculus clearance rate,urinary infection and the oral administration of painkillers were compared after 4 weeks of treatment in the 3 groups.Results The scores of lower urinary tract symptoms,body pain and general health after 1 week of treatment,and the scores of lower urinary tract symptoms,body pain,general health and work performance after 2 and 4 weeks of treatment were lower than those before treatment in the 3 groups(P<0.01).The scores of lower urinary tract symptoms and body pain in the moxibustion group after 1,2 and 4 weeks of treatment were lower than those in the blank control group and the placebo moxibustion group(P<0.01,P<0.05)respectively.The score of general health in the moxibustion group was lower than that in the blank control group after 1 week of treatment(P<0.01),and lower than those of the blank control group and the place
作者
陈浩
王赟
王志民
张誉
赵润璞
CHEN Hao;WANG Yun;WANG Zhi-min;ZHANG Yu;ZHAO Run-pu(Graduate School of Henan University of CM,Zhengzhou 450046,China;Urology Department of First Affiliated Hospital of Henan University of CM,Zhengzhou 450099)
出处
《中国针灸》
CAS
CSCD
北大核心
2023年第11期1251-1256,共6页
Chinese Acupuncture & Moxibustion
基金
河南省中医药科学研究专项课题:2023ZY2050。
关键词
输尿管支架管综合征
输尿管镜碎石术
艾灸
坦索罗辛
安慰灸
随机对照试验
ureteral stent-related symptoms
ureteroscopic lithotripsy
moxibustion
tamsulosin
placebo moxibustion
randomized controlled trial(RCT)