摘要
目的分析突发性聋患者的脑白质病变程度,探讨脑白质高信号对突发性聋预后的影响。方法回顾性收集2021年1月至2021年12月就诊于首都医科大学附属北京天坛医院的143名单侧突发性聋患者的临床资料,根据Fazekas量表评分进行分组,比较各组治疗效果,分析影响突发性聋预后的危险因素。结果0分组72例(50.35%),1分组63例(44.01%),2分组8例(5.59%)。各组患者的患侧初始听阈差异无统计学意义(P>0.05)。0分组与1分组、0分组与2分组患者年龄差异有统计学意义(P<0.01)。各组治疗前及治疗后听力阈值比较,差异均有统计学意义(P<0.01)。0分组、1分组、2分组的痊愈率差异有统计学意义(P<0.01)。年龄、患侧初始听阈是影响痊愈的危险因素。结论脑白质高信号及伴随的心脑血管危险因素可能影响突发性聋对治疗的反应。控制突发性聋患者的心脑血管异常,有助于获得较好的预后。
Objective We aimed to analyze the patient characteristics in accordance with white matter lesions and confirm whether white matter hyperintensity affect final treatment outcomes in sudden sensorineural hearing loss.Methods Medical records of 143 patients treated for unilateral sudden sensorineural hearing loss in Beijing Tiantan Hospital,Capital Medical University from January 2021 to December 2021 were collected.The severity of white matter hyperintensity was assessed with the Fazekas scale.The therapeutic effect of all groups was compared,and the risk factors affecting the prognosis of sudden deafness were analyzed.Results According to the score of Fazekas scale,72 cases(50.35%)were grouped in score of 0 group,63 cases(44.01%)in score of 1 group,and 8 cases(5.59%)in score of 2 group.There was no significant difference in the initial hearing level on the affected side among all groups(P>0.05).There were significant differences in age between group 0 and group 1,group 0 and group 2(P<0.01).There were significant differences in hearing threshold between all groups before and after treatment(P<0.01).The difference of recovery rate in group 0,group 1 and group 2 was statistically significant(P<0.01).Age and initial hearing threshold of affected side were important prognostic factors for complete recovery.Conclusion White matter hyperintensity and associated cardiovascular and cerebrovascular risk factors may affect the response of sudden sensorineural hearing loss to treatment.The control of cardiac and cerebrovascular abnormalities in patients with sudden sensorineural hearing loss is helpful to obtain a better prognosis.
作者
丁玉静
郭翠翠
王璞
苏录
王咏峰
夏寅
DING Yu-jing;GUO Cui-cui;WANG Pu;SU Lu;WANG Yong-feng;XIA Yin(Department of Otorhinolaryngology Head and Neck Surgery,Beijing Tiantan Hospital,Capital Medical University,Beijing 100070,China 2.Department of Radiology,Beijing Tiantan Hospital,Capital Medical University,Beijing 100070,China 3.Department of Otorhinolaryngology Head and Neck Surgery,Changji Branch,The First Affiliated Hospital of Xinjiang Medical University,Changji 831100,Xinjiang,China)
出处
《中国CT和MRI杂志》
2023年第11期4-7,共4页
Chinese Journal of CT and MRI
基金
北京市自然科学基金青年项目(7234361)。
关键词
突发性聋
脑白质高信号
预后
Sudden Sensorineural Hearing Loss
White Matter Hyperintensity
Prognosis