摘要
目的观察腰椎椎体^(99)Tc^(m)-亚甲基二膦酸盐(MDP)SPECT/CT定量代谢参数与患者一般资料的相关性。方法前瞻性对45例(男22例、女23例)未累及腰椎的恶性肿瘤患者行全身骨显像及腰椎SPECT/CT,在SPECT/CT图中于腰椎处放置感兴趣区容积(VOI),获得最大标准摄取值(SUVmax)、平均标准摄取值(SUVmean)、骨代谢总体积(MBV)及骨摄取总量(TBU);采用Pearson相关性分析观察腰椎椎体代谢参数与患者一般资料,包括年龄、身高及体质量的相关性。结果腰椎椎体SUVmax与患者身高、体质量及年龄均呈正相关(r=0.196、0.189、0.227,P均<0.05);SUVmean与身高、年龄呈正相关(r=0.135、0.133,P均<0.05),与体质量无明显相关性(P>0.05);MBV(r=0.221、0.583、0.410)、TBU(r=0.205、0.441、0.280)与年龄、身高及体质量均呈正相关(P均<0.05)。男性与女性腰椎椎体SUVmax、MBV及TBU差异均有统计学意义(P均<0.05),而SUVmean差异无统计学意义(P>0.05)。结论腰椎椎体^(99)Tc^(m)-MDP SPECT/CT定量代谢参数与年龄、性别及体质量相关。
Objective To observe the correlations of^(99)Tc^(m)-methylene diphosphonate(MDP)SPECT/CT quantitative metabolic parameters of lumbar vertebrae with patients'general data.Methods A total of 45 malignant tumor patients(22 males and 23 females)without bone involvement were prospectively enrolled,and whole body bone imaging and lumbar spine SPECT/CT were performed.Based on SPECT/CT images,the volumes of interest(VOI)were placed on lumbar vertebrae,and the maximum standard uptake value(SUV max),mean standard uptake value(SUV mean),metabolic bone volume(MBV)and total bone uptake(TBU)were measured.Pearson correlation analysis was used to observe the correlations of metabolic parameters of lumbar vertebrae with patients'general data,including age,height and body mass.Results SUV max of lumbar vertebrae were positively correlated with height,body mass and age(r=0.196,0.189,0.227,all P<0.05),while SUV mean were positively correlated with height and age(r=0.135,0.133,both P<0.05)but not significantly correlated with body mass(P>0.05).MBV(r=0.221,0.583,0.410)and TBU(r=0.205,0.441,0.280)of lumbar vertebrae were all positively correlated with age,height and body mass(all P<0.05).There were significant differences of SUV max,MBV and TBU of lumbar vertebrae between males and females(all P<0.05),but not of SUV mean(P>0.05).Conclusion^(99)Tc^(m)-MDP SPECT/CT quantitative metabolic parameters of lumbar vertebrae were related to patients'age,gender and body mass.
作者
郑璐
胡玉敬
张新超
田丛娜
李康
蔡晓雨
刘家乐
边艳珠
ZHENG Lu;HU Yujing;ZHANG Xinchao;TIAN Congna;LI Kang;CAI Xiaoyu;LIU Jiale;BIAN Yanzhu(Department of Nuclear Medicine,Hebei General Hospital,Shijiazhuang 050051,China;Hebei Provincial Key Laboratory of Cerebral Networks and Cognitive Disorders,Shijiazhuang 050051,China)
出处
《中国医学影像技术》
CSCD
北大核心
2023年第11期1706-1709,共4页
Chinese Journal of Medical Imaging Technology
关键词
腰椎
体层摄影术
发射型计算机
单光子
前瞻性研究
lumbar vertebrae
tomography,emission-computed,single-photon
prospective studies
