摘要
目的:分析剪切波弹性成像(SWE)的定量和定性指标鉴别乳腺良恶性病变的诊断效能以及定量指标与肿瘤病理分期(pTNM)的相关性。方法:选取医院收治的150例(159个病灶)乳腺病变患者,均行超声SWE检查,检测并记录剪切波速度最大值(SWV_(max))、剪切波速度最小值(SWV_(min))以及SWV_(max)与SWV_(min)的差值(ΔSWV)定量指标,以及黑洞征、硬环征、彩色弹性硬度(Ecol)、肿物的弹性形状(Esha)、肿物的弹性均匀性(Ehomo)及SWE视觉模式分类的定性指标,并通过Logistic回归分析上述指标与乳腺恶性病变的相关性。结果:Logistic回归分析显示,ΔSWV和视觉模式与肿瘤良恶性关系密切。受试者工作特征(ROC)曲线分析显示,ΔSWV的ROC曲线下面积(AUC)为0.804,灵敏度为75.2%,特异度为82.4%,截断值为2.26 m/s;视觉模式AUC为0.792,灵敏度为94.4%,特异度为50.8%;联合指标的AUC为0.881,灵敏度为80.1%,特异度为88.6%。相关性分析显示,ΔSWV、视觉模式与pTNM分期均呈正相关(r=0.314,r=0.307;P<0.05)。结论:SWE指标中的ΔSWV和视觉模式与肿瘤良恶性密切相关,两者联合诊断效能最高。通过SWE测定可以评估患者病情严重程度以及指导治疗。
Objective:To analyze the diagnostic efficiency of the quantitative and qualitative indicators of shear wave elastography(SWE)in differentiating benign and malignant lesions of breast,and the correlation between quantitative indicators and pathological tumor node metastasis(pTNM)staging.Methods:A total of 150 patients with breast lesions(159 lesions)who admitted to hospital were selected,and all of them underwent ultrasound SWE exa_(min)ation.The quantitative indicators included SWV_(max)imum value(SWV_(max)),the SWV_(min)imum value(SWV_(min))and the difference(ΔSWV)of them were detected and recorded.The qualitative indicators included black hole sign,hard ring sign,color elastic hardness(Ecol),elastic shape of the tumor(Esha),elastic homogeneity of the tumor(Ehomo)and classification of SWE visual mode also were detected and recorded.Logistic regression analysis was performed to analyze the correlation between the above indicators and malignant lesions of breast.Results:Logistic regression analysis showed thatΔSWV and visual mode were closely related to benign and malignant tumors.The receiver operating characteristic(ROC)curve analysis showed that the area under curve(AUC)value ofΔSWV was 0.804,and the sensitivity,specificity and cut-off value of that were respectively 75.2%,82.4%and 2.26m/s.The AUC value,sensitivity and specificity of visual mode were respectively 0.792,94.4%and 50.8%.The AUC value,sensitivity and specificity of combined indicators were respectively 0.881,80.1%and 88.6%.Correlation analysis showed that bothΔSWV and visual mode appeared positive correlation with pTNM staging(r=0.314,r=0.307,P<0.05),respectively.Conclusion:BothΔSWV and visual mode of SWE indicators are closely related to benign and malignant tumors,and the combination of them has the highest diagnostic efficiency.SWE measurement can be used to assess the severity of the disease conditions of patients and to guide treatment for patients.
作者
伍丽媛
黄冬花
李敏
陈玉婷
谢盛妹
WU Li-yuan;HUANG Dong-hua;LI Min(Department of Ultrasonography,Qionghai People's Hospital,QiongHai 571400,China;不详)
出处
《中国医学装备》
2023年第11期72-76,共5页
China Medical Equipment
基金
海南省卫生健康行业科研项目(20A200087)“剪切波弹性成像对乳腺良恶性病变的鉴别诊断”。
