摘要
目的探讨自拟内异方联合妇科灌肠液对子宫腺肌症的疗效及对子宫肌层CDFI参数的影响。方法选取2020年11月-2021年12月于茂名市中医院妇产科医治的子宫腺肌症患者共90例,随机分成治疗A组、治疗B组和对照组,各30例。对照组予以散结镇痛胶囊,治疗A组予以自拟内异方联合妇科灌肠液,治疗B组予以自拟内异方治疗。比较三组中医证候积分、临床疗效、子宫体积大小和肌层多普勒血流信号参数变化情况。结果三组治疗3个月后、停药3个月中医证候积分均低于治疗前,治疗A组、B组中医证候积分低于对照组,且治疗A组低于治疗B组,差异有统计学意义(P<0.05);治疗A组总有效率高于治疗B组及对照组,差异有统计学意义(P<0.05);三组治疗3个月后子宫体积均小于治疗前,治疗A组小于治疗B组及对照组,且停药3个月后治疗A组子宫体积小于治疗前,而治疗B组及对照组体积大于治疗前,但差异无统计学意义(P>0.05);三组治疗3个月后PI、RI值均低于治疗前,且治疗A组、B组低于对照组,治疗A组低于治疗B组(P<0.05);停药3个月后,治疗A组及B组PI、RI值仍低于治疗前,且治疗A组低于治疗B组,而对照组PI、RI值较治疗前升高,差异有统计学意义(P<0.05)。结论自拟内异方联合妇科灌肠液相较于单纯的中药或者中成药口服更能有效改善气滞血瘀型子宫腺肌症患者中医证候,且停药后症状不易反弹,能够降低子宫肌层多普勒血流信号中PI、RI值,改善子宫动脉血流情况,提高气滞血瘀型子宫腺肌症患者临床疗效。
Objective To investigate the effect of self-made Neiyi prescription combined with gynecological enema on adenomyosis and its effect on CDFI parameters of myometrium.Methods A total of 90 patients with adenomyosis who were treated in the Department of Obstetrics and Gynecology of Maoming Hospital of Traditional Chinese Medicine from November 2020 to December 2021 were randomly divided into treatment group A,treatment group B and control group,with 30 patients each group.The control group was treated with Sanjie Zhentong capsule,the treatment group A was treated with self-made Neiyi Decoction combined with gynecological enema,and the treatment group B was treated with self-made Neiyi Decoction.The changes of TCM syndrome scores,clinical efficacy,uterine volume and muscular Doppler blood flow signal parameters were compared among the three groups.Results The TCM syndrome scores of the three groups after 3 months of treatment and 3 months after drug withdrawal were lower than those before treatment,while the TCM syndrome scores of the treatment group A and group B were lower than those of the control group,and the treatment group A was lower than the treatment group B,the difference was statistically significant(P<0.05).The total effective rate of treatment group A was higher than that of treatment group B and control group,and the difference was statistically significant(P<0.05).After 3 months of treatment,the uterine volume of the three groups was smaller than that before treatment,and the treatment group A was smaller than the treatment group B and the control group,After 3 months of withdrawal,the uterine volume of the treatment group A was smaller than that before treatment,while the volume of the treatment group B and the control group was larger than that before treatment,but the difference was not statistically significant(P>0.05).After 3 months of treatment,the PI and RI values of the three groups were lower than those before treatment,and the treatment group A and group B were lower than the control group,a
作者
张帆
王文娜
周华珺
ZHANG Fan;WANG Wen-na;ZHOU Hua-jun(Department of Obstetrics and Gynecology,Maoming Hospital of Guangzhou University of Traditional Chinese Medicine/Maoming Hospital of Traditional Chinese Medicine,Maoming 525000,Guangdong,China)
出处
《医学信息》
2023年第22期140-143,147,共5页
Journal of Medical Information
基金
茂名市科技专项(编号:茂科字﹝2020﹞57号)。
关键词
自拟内异方
妇科灌肠液
子宫腺肌症
Self-made Neiyi recipe
Gynecological enema solution
Adenomyosis
