摘要
目的:探讨股骨转子间粉碎性骨折患者采用活血祛瘀汤与股骨近端抗旋转髓内钉(PFNA)内固定手术治疗的临床效果。方法:选择2021年5月—2022年5月将乐县总医院收治的100例股骨转子间粉碎性骨折患者作为研究对象,使用随机数表法将其分为对照组和观察组,各50例。对照组采用PFNA内固定手术治疗,观察组采用PFNA内固定手术与活血祛瘀汤联合治疗。比较两组的临床总有效率、并发症发生率及治疗前后的骨代谢指标、生活质量评分。结果:观察组临床总有效率高于对照组,差异有统计学意义(P<0.05)。治疗前,两组血清骨碱性磷酸酶(BALP)、骨钙素(BGP)、Ⅰ型前胶原羧基端肽(PⅠCP)、Ⅰ型胶原羧基端肽β特殊序列(β-CTX)和总Ⅰ型前胶原氨基端延长肽(t-PⅠNP)比较,差异无统计学意义(P>0.05);治疗后,观察组BALP、BGP和PⅠCP均高于对照组,而β-CTX和t-PⅠNP低于对照组,差异有统计学意义(P<0.05)。治疗前,两组健康调查简表(SF-36)各项评分比较,差异无统计学意义(P>0.05);治疗后,观察组社会功能、情感职能、精神健康、生理机能、生理职能、精力、躯体疼痛、一般健康状况评分均高于对照组,差异有统计学意义(P<0.05)。观察组并发症发生率低于对照组,差异有统计学意义(P<0.05)。结论:股骨转子间粉碎性骨折患者采用活血祛瘀汤与PFNA内固定手术联合治疗的效果较显著,不仅能有效改善其骨代谢指标,还能提高其生活质量,降低其并发症发生率。
Objective:To investigate the clinical effect of Huoxue Quyu Decoction and proximal femoral nail antirotation(PFNA)internal fixation in treatment of intertrochanteric comminuted fracture of femur.Method:A total of 100 patients with intertrochanteric comminuted fracture of femur treated in Jiangle County General Hospital from May 2021 to May 2022 were selected as the study objects,and they were divided into control group and observation group by random number table method,with 50 cases in each group.The control group was treated with PFNA internal fixation,and the observation group was treated with PFNA internal fixation and Huoxue Quyu Decoction.The clinical total effective rate,complication rate,bone metabolism index and quality of life score before and after treatment were compared between the two groups.Result:The total clinical effective rate of observation group was higher than that of control group,the difference was statistically significant(P<0.05).Before treatment,there were no significant differences in serum bone alkaline phosphatase(BALP),osteocalcin(BGP),typeⅠprocollagen carboxy-terminal peptide(PⅠCP),β-carboxyⅠterminal peptide(β-CTX)and total procollagenⅠN-terminal propeptide(t-PⅠNP)between the two groups(P>0.05).After treatment,BALP,BGP and PⅠCP in observation group were higher than those in the control group,whileβ-CTX and t-PⅠNP were lower than those in the control group,the differences were statistically significant(P<0.05).Before treatment,there were no significant differences in scores of the MOS item short from health survey(SF-36)between the two groups(P>0.05).After treatment,the scores of social function,emotional function,mental health,physiological function,role-physical,energy,body pain and general health status in the observation group were higher than those in the control group,and the differences were statistically significant(P<0.05).The incidence of complications in the observation group was lower than that in the control group,the difference was statistically signif
作者
杨亨利
王新忠
熊福
YANG Hengli;WANG Xinzhong;XIONG Fu(Jiangle County General Hospital,Jiangle 353300,China;不详)
出处
《中外医学研究》
2023年第29期5-9,共5页
CHINESE AND FOREIGN MEDICAL RESEARCH
关键词
股骨转子间粉碎性骨折
活血祛瘀汤
股骨近端抗旋转髓内钉内固定手术
骨代谢指标
并发症
Intertrochanteric comminuted fracture of femur
Huoxue Quyu Decoction
Proximal femoral nail antirotation internal fixation
Bone metabolism index
Complication
