摘要
随着恶性肿瘤发病年龄的年轻化和女性生育年龄的普遍推迟,生育力保护已成为临床制定肿瘤患者治疗方案时常需权衡和解决的难题,评估恶性肿瘤患者具体情况并制定生育力保护方案,已成为现代妇科肿瘤工作的重要内容.本文总结了妇科肿瘤手术、化疗、放疗对生育力的影响,不同类型妇科肿瘤(宫颈癌、内膜癌、卵巢癌)及不同群体(成年、儿童、特殊人群)治疗过程中生育力保护的新进展新理念,并探讨了可于保护女性生育力的新技术方法及伦理要点.
As the age at which females consider childbearing is increasingly delayed,there is a growing demand for fertility preservation among patients with gynecological malignancies.Assessing individual patient conditions and formulating fertility preservation strategies has become a crucial aspect of modern gynecologic oncology.This review comprehensively explores the implications of gynecological cancer surgery,chemotherapy,and radiotherapy on fertility.It also delves into emerging developments and progressive concepts in fertility preservation tailored to various gynecological cancers(such as cervical cancer,endometrial cancer,and ovarian cancer)and diverse populations(including adults,children,and special cases).Additionally,the article highlights innovative technological approaches aimed at safeguarding female fertility while addressing the associated ethical considerations.
作者
万姣
黄优优
杨景
黄魁
陈嫣
刘双
刘巧
欧阳佩琳
唐毅
张璞
赵璟
陈天敏
孟胜君
蒋丹
龚颖萍
田畦
舒楚强
WAN Jiao;HUANG YouYou;YANG Jing;HUANG Kui;CHEN Yan;LIU Shuang;LIU Qiao;OUYANG PeiLin;TANG Yi;ZHANG Pu;ZHAO Jing;CHEN TianMin;MENG ShengJun;JIANG Dan;GONG YingPing;TIAN Qi;SHU ChuQiang(Department of Gynecologic Oncology and Cervical Lesion,The Affiliated Maternal and Child Health Care Hospital(Hunan Provincial Maternal and Child Care Hospital),Hengyang Medical School,University of South China,Changsha 410008,China)
出处
《中国科学：生命科学》
CSCD
北大核心
2023年第10期1439-1454,共16页
Scientia Sinica(Vitae)
基金
国家自然科学基金(批准号:3210010962)
湖南省自然科学基金(批准号:2022JJ70092,2022JJ70093)
湖南省科技创新平台与人才计划——湖南省宫颈癌防治临床医学研究中心基金(批准号:2021SK4021)
湖南省普惠性政策与创新环境建设计划——临床医疗技术创新引导项目(批准号:2021SK50612,2021SK50608,2020SK50605)资助。
关键词
妇科恶性肿瘤
生育力保护
辅助生殖技术
gynecologic cancer
fertility preserving
assisted reproductive technology
