摘要
艾滋病病毒PrEP是在发生高危行为之前服用特定抗病毒药物预防HIV感染的方法,PrEP的有效性主要取决于服药者的依从性。本文综述了PrEP用药依从性及影响因素研究进展,服药人群中依从的人数占比在14.3%~74%左右,总体依从率约为23%~66%。PrEP用药依从性受忘记服药和忘记带药、污名化、自我感知HIV感染风险、经济支持、医保和服务水平、家庭和同伴的支持等因素影响,可针对这些因素制定实施干预策略,以有效提高服药者依从性。
HIV pre-exposure prophylaxis(PrEP)is the intervention of using antiviral drugs to prevent HIV infection before HIV exposure.The effectiveness of PrEP depends largely on users'adherence.This paper reviewed the research progress of PrEP adherence and influencing factors.The users with good adherence accounted for 14.3%-74%in the study populations.The overall adherence rate was 23%-66%.The PrEP adherence can be affected by factors such as forgetting to take or carry medication,stigma,self-perceived risk of HIV infection,financial support,health insurance,service levels,as well as family and partner support.More researches are needed to target strategies and measures to optimize PrEP adherence in the future.
作者
朱玉荣
徐杰
ZHU Yurong;XU Jie(National Center for AIDS/STD Control and Prevention,Chinese Center for Disease Control and Prevention,Beijing 102206,China)
出处
《中国艾滋病性病》
CAS
CSCD
北大核心
2023年第8期931-934,共4页
Chinese Journal of Aids & STD
