摘要
目的分析前列腺癌(PCa)定性诊断中3.0 T磁共振成像(MRI)多序列联合扫描的准确率。方法回顾性研究本院2019年1月至2022年1月接诊的60例高度疑似PCa患者,给予3.0 T MRI多序列检查,分别是T_(1)加权成像(T_(1)WI)、T_(2)加权成像(T_(2)WI)、弥散加权成像(DWI),将病理活检穿刺结果作为本次研究的金标准,对比T_(1)WI、T_(2)WI、DWI单独与联合诊断准确率、灵敏度、特异度,Kappa检验T_(1)WI、T_(2)WI、DWI单独及联合诊断与金标准的一致性,对比良性前列腺增生(BPH)组、PCa组表观扩散系数(ADC值)、多模态MRI参数。结果T_(1)WI、T_(2)WI、DWI联合诊断准确率(96.7%)、灵敏度(88.9%)均高于T_(1)WI(76.7%、22.2%)、T_(2)WI(76.7%、31.2%)、DWI单独诊断(71.7%、22.2%),差异有统计学意义(P<0.05)。T_(1)WI、T_(2)WI、DWI联合诊断特异度(100%)与T_(1)WI、T_(2)WI、DWI单独诊断(100%、97.6%、92.9%)比较,差异无统计学意义(P>0.05),T_(1)WI、T_(2)WI、DWI与病理活检穿刺一致性一般(Kappa值=0.567、0.597、0.577),T_(1)WI+T_(2)WI+DWI与病理活检穿刺一致性较好(Kappa值=0.786,P<0.05)。PCa组ADC值、Tmax均低于BPH组,PCa组Rmax、SImax均高于BPH组,差异均具有统计学意义(P<0.05)。结论3.0 T MRI T_(1)WI、T_(2)WI、DWI多序列联合扫描可提高PCa诊断准确率,同时提供ADC值等MRI参数,为临床鉴别良、恶性病灶提供更多参考依据。
Objective To analyze the accuracy of 3.0T MRI multi-sequence combined scanning in the qualitative diagnosis of prostate cancer(PCa).Methods A retrospective study of 60 highly suspected PCa patients admitted to our hospital from January 2019 to January 2022 was given 3.0T MRI multi-sequence examinations,including T_(1)WI sequence,T_(2)WI sequence,and DWI sequence.Pathological biopsy was used as the gold standard to compare the diagnostic accuracy,sensitivity,and specificity of T_(1)WI,T_(2)WI,and DWI alone and in combination.Apparent diffusion coefficient(ADC value),multimodal MRI parameters in PCa group and benign prostatic hyperplasia(BPH)group were compared.Results The combined diagnostic accuracy(96.7%)and sensitivity(88.9%)of T_(1)WI,T_(2)WI,and DWI were higher than those of T_(1)WI(76.7%,22.2%),T_(2)WI(76.7%,31.2%),and DWI alone(71.7%,22.2%)(P<0.05).There was no significant difference in diagnostic specificity between T_(1)WI,T_(2)WI combined DWI(100%)and with T_(1)WI,T_(2)WI,DWI alone(100%,97.6%,92.9%)(P>0.05).The consistency of T_(1)WI,T_(2)WI,DWI and pathology was general(Kappa value=0.567,0.597,0.577),and the consistency of T_(1)WI+T_(2)WI+DWI and pathological biopsy was better(Kappa value=0.786,P<0.05).The ADC value and Tmax in the PCa group were lower than those in the BPH group,and the Rmax and SImax in the PCa group were higher than those in the BPH group,both differences were statistically significant(P<0.05).Conclusion 3.0 T MRI T_(1)WI,T_(2)WI,DWI multi-sequence combined scanning can improve the diagnostic accuracy of PCa,and provide MRI parameters such as ADC value,providing more reference for clinical differentiation of benign and malignant lesions.
作者
田金炎
Tian Jinyan(Department of Radiology,Luoyang Sixth People′s Hospital,Henan471003,China)
出处
《实用医学影像杂志》
2023年第4期270-274,共5页
Journal of Practical Medical Imaging
关键词
磁共振成像
前列腺肿瘤
表观扩散系数
诊断效能
Magnetic resonance imaging
Prostatic neoplasms
Apparent diffusion coefficient
Diagnostic performance
