摘要
目的探讨3.0T磁共振成像(MRI)多b值磁共振弥散加权成像(DWI)在前列腺增生和前列腺癌患者中的鉴别诊断价值。方法选取2018年1月至2020年3月于我院就诊的120例前列腺疾病患者作为研究对象,对患者实施计算机断层扫描(CT)检查、MRI平扫、3.0T MRI多b值DWI检查;以穿刺活检病理诊断结果为金标准,比较CT、MRI平扫、3.0T MRI多b值DWI对前列腺癌的诊断效能,并分析CT、MRI平扫、3.0T MRI多b值DWI与穿刺活检病理诊断结果之间的一致性。根据穿刺活检病理诊断结果将患者分为前列腺癌组与前列腺增生组,比较两组患者在不同b值DWI图像中的表观弥散系数(ADC)。结果以穿刺活检病理诊断结果为金标准,3.0T MRI多b值DWI在前列腺癌诊断中的灵敏度、特异度、准确度、阳性预测值、阴性预测值均高于CT、MRI平扫(P<0.05)。3.0T MRI多b值DWI诊断结果与穿刺活检病理诊断结果之间呈高度一致,而CT、MRI平扫诊断结果均与穿刺活检病理诊断结果之间呈中度一致。在不同b值DWI图像中,前列腺癌组的ADC值均低于前列腺增生组,差异具有统计学意义(P<0.05)。结论3.0T MRI多b值DWI用于前列腺癌、前列腺增生中的鉴别诊断价值良好,可对前列腺癌与前列腺增生进行灵敏、准确地鉴别诊断,还可利用DWI图像中的ADC值实现对前列腺癌与前列腺增生的量化诊断。
Objective To investigate the differential diagnosis value of 3.0 T magnetic resonance imaging(MRI)multi-b value diffusion weighted imaging(DWI)in patients with prostatic hyperplasia and prostate cancer.Methods From January2018 to March 2020,120 patients with prostate diseases treated in our hospital were selected as the study objects,the patients were examined by computed tomography(CT),MRI plain scan and 3.0 T MRI multi-b value DWI.The pathological diagnosis result of puncture biopsy was as the gold standard,the diagnostic efficacy of CT,MRI plain scan,3.0 T MRI multi-b value DWI in prostate cancer were compared,and the consistency between CT,MRI plain scan,3.0 T MRI multi-b value DWI and biopsy pathological diagnosis results were analyzed.The patients were divided into prostate cancer group and prostate hyperplasia group according to the pathological diagnosis result of puncture biopsy,and the apparent dispersion coefficient(ADC)of DWI images with different b values was compared between the two groups.Results The pathological diagnosis result of puncture biopsy was as the gold standard,and the sensitivity,specificity,accuracy,positive predictive value and negative predictive value of 3.0 T MRI multi-b value DWI were higher than those of CT and MRI plain scan(P<0.05).The diagnosis result of 3.0 T MRI multi-b value DWI was highly consistent with the pathological diagnosis result of puncture biopsy,while the diagnosis results of CT and MRI plain scan were moderately consistent with the pathological diagnosis result of puncture biopsy.In different b value DWI images,ADC value of the prostate cancer group were lower than those of the prostatic hyperplasia group,and the differences were statistically significant(P<0.05).Conclusion The 3.0 T MRI multi-b value DWI has a good differential diagnostic value in prostate cancer and prostatic hyperplasia,it can be used for sensitive and accurate differential diagnosis of prostate cancer and benign prostatic hyperplasia.The ADC value in DWI image can also be used to realize t
作者
张利
赵明增
高淑艳
ZHANG Li;ZHAO Mingzeng;GAO Shuyan(Yan'an City Hospital of TCM,Yan'an 716000;Xi'an XD Group Hospital,Xi'an 710077;Traditional Chinese Medicine Hospital of Yulin,Yulin 719000,China)
出处
《临床医学研究与实践》
2020年第33期121-123,共3页
Clinical Research and Practice
基金
西安市卫生和计划生育委员会科技计划项目(No.2016D070)。
关键词
前列腺癌
前列腺增生
计算机断层扫描
磁共振成像
弥散加权成像
prostate cancer
prostatic hyperplasia
computed tomography
magnetic resonance imaging
diffusion weighted imaging
