摘要
目的分析超重及肥胖体检人群定量CT所测体脂分布与血脂的相关性。方法本研究为回顾性队列研究, 采用整体抽样法选取2021年1—12月于河南省人民医院健康管理学科行胸部CT联合定量CT检查的3 463例体检人群为研究对象, 根据体重指数18.5~<24.0 kg/m2、24.0~<28.0 kg/m2和≥28.0 kg/m2分为正常组(1 424例)、超重组(1 531例)和肥胖组(508例)。收集3组一般资料、血脂指标和定量CT所测不同部位体脂分布(皮下脂肪面积、内脏脂肪面积、腹部总脂肪面积、肝脏脂肪含量、肌肉脂肪含量), 采用单因素方差分析比较体脂分布及血脂指标差异, 采用Pearson相关分析评估体脂分布与血脂的相关性。结果肥胖组皮下脂肪面积、内脏脂肪面积、腹部总脂肪面积、肝脏脂肪含量、肌肉脂肪含量、总胆固醇、低密度脂蛋白胆固醇(LDL-C)和甘油三酯均显著高于正常组和超重组[男性:(152.80±49.27)比(72.94±22.68)、(103.79±28.30)cm2, (287.95±57.55)比(156.36±49.40)、(224.67±53.10)cm2, (440.75±72.44)比(229.31±62.01)、(328.46±62.77)cm2, (12.92±8.61)%比(6.82±3.31)%、(9.39±4.88)%, (9.06±9.34)%比(4.55±5.06)%、(6.70±6.73)%, (6.52±0.94)比(4.87±1.03)、(6.27±0.96)mmol/L, (3.05±0.76)比(2.92±0.86)、(2.97±0.77)mmol/L, (2.34±1.42)比(1.53±0.82)、(1.99±1.28)mmol/L;女性:(213.82±46.87)比(104.69±30.62)、(155.05±34.90)cm2, (184.88±46.54)比(90.67±34.09)、(138.92±42.06)cm2, (398.71±71.28)比(195.37±55.32)、(293.97±57.05)cm2, (11.36±6.34)%比(5.51±3.02)%、(7.98±4.77)%, (7.44±7.60)%比(3.70±3.90)%、(5.56±5.94)%, (5.27±0.96)比(5.04±0.86)、(5.11±0.96)mmol/L, (3.26±0.84)比(2.92±0.79)、(3.01±0.74)mmol/L, (1.74±0.69)比(1.27±0.65)、(1.57±0.77)mmol/L], 高密度脂蛋白胆固醇(HDL-C)显著低于正常组和超重组[男性:(1.17±0.19)比(1.38±0.28)、(1.25±0.25)mmol/L;女性:(1.36±0.22)比(1.59±0.32)、(1.42±0.27)mmol/L](均P<0.001)。男性超重组内脏脂肪面积、腹部�
Objective To analyze the correlation between quantified body fat distribution measured by computed tomography(CT)and blood lipids in overweight and obese individuals undergoing physical examinations.Methods In this retrospective cohort study,a total of 3463 physical examination subjects who underwent chest CT combined with quantified CT examination in the Department of Health Management at Henan Provincial People′s Hospital from January to December 2021 were selected using a comprehensive sampling method.The subjects were divided into three groups:normal group(1,424 cases),overweight group(1,531 cases),and obese group(508 cases)based on their body mass index:18.5 to<24.0 kg/m2,24.0 to<28.0 kg/m2,and≥28.0 kg/m2,respectively.General information,blood lipid parameters,and different body fat distributions measured by quantified CT(subcutaneous fat area,visceral fat area,total abdominal fat area,liver fat content,muscle fat content)were collected in the three groups.One-way analysis of variance was used to compare differences in body fat distribution and blood lipid parameters,and Pearson correlation analysis was performed to evaluate the correlation between body fat distribution and blood lipids.Results In the obese group,compared to the normal and overweight groups,subcutaneous fat area,visceral fat area,total abdominal fat area,liver fat content,muscle fat content,total cholesterol,low-density lipoprotein cholesterol(LDL-C),and triglyceride levels were significantly higher[males:(152.80±49.27)vs(72.94±22.68),(103.79±28.30)cm2;(287.95±57.55)vs(156.36±49.40),(224.67±53.10)cm2;(440.75±72.44)vs(229.31±62.01),(328.46±62.77)cm2;(12.92±8.61)%vs(6.82±3.31)%,(9.39±4.88)%;(9.06±9.34)%vs(4.55±5.06)%,(6.70±6.73)%;(6.52±0.94)vs(4.87±1.03),(6.27±0.96)mmol/L;(3.05±0.76)vs(2.92±0.86),(2.97±0.77)mmol/L;(2.34±1.42)vs(1.53±0.82),(1.99±1.28)mmol/L;females:(213.82±46.87)vs(104.69±30.62),(155.05±34.90)cm2;(184.88±46.54)vs(90.67±34.09),(138.92±42.06)cm2;(398.71±71.28)vs(195.37±55.32),(293.97±57.05)cm2
作者
孙永兵
周阳
戚昕
李中林
邹智
武肖玲
周菁
屈敏
张潇琳
王勇
窦社伟
刘红明
闫峰山
朱嘉栋
李永丽
Sun Yongbing;Zhou Yang;Qi Xin;Li Zhonglin;Zou Zhi;Wu Xiaoling;Zhou Jing;Qu Min;Zhang Xiaolin;Wang Yong;Dou Shewei;Liu Hongming;Yan Fengshan;Zhu Jiadong;Li Yongli(Department of Medical Imaging,People′s Hospital of Zhengzhou University/Henan Provincial People′s Hospital,Zhengzhou 450003,China;Department of Clinical Medicine,Xinxiang Medical College,People′s Hospital of Zhengzhou University/Henan Provincial People′s Hospital,Zhengzhou 450003,China;Department of Nuclear Medicine,People′s Hospital of Zhengzhou University/Henan Provincial People′s Hospital,Zhengzhou 450003,China;Henan Key Laboratory of Chronic Disease Health Management,People′s Hospital of Zhengzhou University/Henan Provincial People′s Hospital,Zhengzhou 450003,China;Department of General Medicine,People′s Hospital of Zhengzhou University/Henan Provincial People′s Hospital,Zhengzhou 450003,China)
出处
《中华健康管理学杂志》
CAS
CSCD
2023年第9期698-704,共7页
Chinese Journal of Health Management
基金
国家自然科学基金(82071884)
河南省中青年卫生健康科技创新人才项目(YXKC2020004)
河南省医学科技攻关联合共建项目(LHGJ20200060)。
关键词
定量CT
体格检查
超重
肥胖症
体脂分布
血脂
Quantitative CT
Physical examination
Overweight
Obesity
Body fat distribution
Blood lipids
