摘要
目的探讨动脉粥样硬化支架植入术后冠状动脉(冠脉)再狭窄的相关危险因素。方法选择2020年1月至2022年1月于重庆医科大学附属大足医院治疗的动脉粥样硬化患者120例进行研究,所有患者均行冠脉支架植入术。随访术后冠脉再狭窄发生情况,收集患者的临床资料,并分析冠脉再狭窄的危险因素,根据随访结果分为再狭窄组(n=21)和对照组(n=99)两组。结果120例动脉粥样硬化支架植入术后患者中,冠脉再狭窄21例(17.50%);单因素分析显示,两组患者性别、年龄、病变支数、饮酒、支架植入部位、左室射血分数(LVEF)比较,差异无统计学意义(P>0.05);两组糖尿病、冠状动脉粥样硬化性心脏病(冠心病)家族史、高血压、吸烟、支架植入数量、支架长度、支架直径、串联支架、规范用药比较,差异有统计学意义(P<0.05)。将术后发生冠脉再狭窄作为因变量,进行多因素非条件Logistic分析结果显示,糖尿病、冠心病家族史、高血压、吸烟、支架植入数量、支架长度、支架直径、串联支架、规范用药均是冠脉支架植入术后冠脉再狭窄的独立危险因素(P<0.05)。所有患者均随访12个月,记录两组急性冠脉事件发生情况,主要表现为心绞痛加重,心肌梗死、心源性猝死,再狭窄组发生率为28.57%,对照组为9.09%,两组比较差异有统计学意义(P=0.014)。结论糖尿病、冠心病家族史、高血压、吸烟、支架植入数量、支架长度、支架直径、串联支架、规范用药均是冠脉支架植入术后冠脉再狭窄的危险因素,临床对于此类患者应引起重视,积极治疗,以改善预后。
Objective To investigate the risk factors related to coronary restenosis after stent implantation for atherosclerosis(AS).Methods AS patients(n=120)were chosen from Dazu Hospital affiliated to Chongqing Medical University from Jan.2020 to Jan.2022,and all patients were received stent implantation.The incidence of postoperative coronary stenosis was followed up,and clinical materials were collected from the patients and the risk factors of coronary stenosis were analyze.The patients were divided,according to follow-up results,into restenosis group(n=21)and control group(n=99).Results Of 120 AS patients,21(17.50%)had coronary restenosis.The single-factor analysis showed that differences in gender,age,diseased vessel numbers,drinking,sites of stent implantation and left ventricular ejection fraction(LVEF)had no statistical significance between 2 groups(P>0.05),and differences in diabetes,family history of coronary heart disease(CHD),hypertension,smoking,number of stents,stent length,stent diameter,series stents and standardized medication had statistical significance(P<0.05).The results of multi-factor non-condition Logistic analysis,taken postoperative coronary restenosis as dependent variable,showed that diabetes,CHD family history,hypertension,smoking,number of stents,stent length,stent diameter,series stents and standardized medication all were independent risk factors of coronary restenosis after coronary stent implantation(P<0.05).All patients were followed up for 12 months to record incidence of acute coronary events,and major acute coronary events included aggravation of angina pectoris,myocardial infarction and sudden cardiac death.The incidence rates of acute coronary events were 28.57%in restenosis group and 9.09%in control group(P=0.014).Conclusion Diabetes,CHD family history,hypertension,smoking,number of stents,stent length,stent diameter,series stents and standardized medication all are risk factors of coronary restenosis after coronary stent implantation.The attention should be paid to and active tre
作者
黄治霞
许中恒
陶黎
Huang Zhixia;Xu Zhongheng;Tao Li(Department of Cardiovascular Medicine,Dazu Hospital,Chongqing Medical University,Chongqing 402360,China;不详)
出处
《中国循证心血管医学杂志》
2023年第7期847-849,共3页
Chinese Journal of Evidence-Based Cardiovascular Medicine
基金
重庆市大足区科技发展项目(DZKJ2022JSYJ-KWXM1011)。
