摘要
目的分析冠状动脉支架再狭窄患者接受紫杉醇药物涂层球囊治疗的可行性。方法采用随机抽样法在2020年1月-2022年6月本院收治的冠状动脉支架再狭窄患者中抽取106例,将入组患者随机编号1~106,分别将奇数编号、偶数编号患者各53例纳入对照组以及观察组。对照组患者采用药物涂层支架治疗,观察组患者采用紫杉醇药物涂层球囊治疗。对比分析两组患者治疗费用、目标血管直径、狭窄程度以及心血管不良事件发生情况。结果治疗费用组间比较,无明显差异(P>0.05)。术前,目标血管直径以及狭窄程度组间比较,无明显差异(P>0.05);术后,目标血管直径组内比较术后高于术前、组间比较观察组高于对照组,狭窄程度组内比较术后低于术前、组间比较观察组低于对照组(P<0.05)。心血管不良事件发生率组间比较,观察组3.77%(2/53)显著低于对照组15.09%(8/53)(P<0.05)。结论对于冠状动脉支架再狭窄患者,采用紫杉醇药物涂层球囊治疗不会额外增加治疗费用,并且可有效扩充病变血管管腔直径,降低狭窄程度,目标血管再通效果理想,且术后心血管不良事件发生率较低。
Objective:To analyze the feasibility of paclitaxel-coated balloon therapy in patients with coronary stent restenosis.Methods:A total of 106 patients with coronary stent restenosis admitted to our hospital from January 2020 to June 2022 were selected by random sampling,and were randomly numbered 1-106,with 53 cases with odd numbers and 53 cases with even number in the control group and the observation group,respectively.Patients in the control group were treated with drug-coated stents,while patients in the observation group were treated with paclitaxel drug-coated balloons.The treatment cost,target vessel diameter,degree of stenosis and incidence of cardiovascular adverse events were compared between the two groups.Results:There was no significant difference in treatment cost between groups(P>0.05).Preoperatively,there was no significant difference in target vessel diameter and degree of stenosis between groups(P>0.05);postoperatively,the target vessel diameter within each group was higher than that before operation;the observation group was higher than that in the control group by comparison among groups;the degree of stenosis within each group was lower than that before operation;the observation group was lower than that in the control group by comparison among groups(P<0.05).The incidence of cardiovascular adverse events was significantly lower in the observation group(3.77%,2/53)than that in the control group(15.09%,8/53)(P<0.05).Conclusion:For patients with coronary stent restenosis,paclitaxel-coated balloon therapy does not increase the cost of treatment,and can effectively enlarge the diameter of the diseased vessel lumen,reduce the degree of stenosis.The effect of target recanalization is satisfactory,and the incidence of postoperative cardiovascular adverse events is low.
作者
刘青平
李娟
彭强
LIU Qing-ping;LI Juan;PENG Qiang(Yichun Second People's Hospital,Yichun Jiangxi 336000,China)
出处
《透析与人工器官》
2024年第1期5-8,共4页
Chinese Journal of Dialysis and Artificial Organs
