摘要
热应激会引起机体生理生化反应的改变,打破氧化-抗氧化体系的平衡,从而造成氧化损伤。与此同时,机体因适应性调控会启动应激防御反应,包括一些非特异性免疫指标、基因/蛋白及激素等水平的变化。文章从鱼类抗氧化能力、基因/蛋白表达水平变化、激素调控机制等方面,归纳总结了热应激对鱼类的危害,并分析了转录组、蛋白组、代谢组和脂质组等组学技术在鱼类热应激上的应用与研究进展,以期为鱼类热应激和抗热应激的研究提供理论参考。
Heat stress can cause changes in physiological and biochemical reactions of the body,and the balance of oxidation-antioxidant system is destroyed,which can cause oxidative damage.Meanwhile,the body will activate the stress defense response due to adaptive regulation,including some non-specific immune indicators,gene/protein and hormone level changes.In this article,the effects of heat stress on fish were summarized from the aspects of antioxidant capacity,changes in gene/protein expression level and hormone regulation mechanism,and the application and research progress of omics technology including transcriptome,proteome,metabolome and lipid on heat stress in fish were analyzed,in order to provide theoretical reference for the study of heat stress and anti-heat stress of fish.
作者
周静
权金强
刘哲
卢军浩
赵桂研
ZHOU Jing;QUAN Jinqiang;LIU Zhe;LU Junhao;ZHAO Guiyan(Gansu Academy of Eco-environmental Sciences,Lanzhou 730020,China;College of Animal Science and Technology,Gansu Agricultural University,Lanzhou 730070,China)
出处
《黑龙江畜牧兽医》
北大核心
2023年第17期29-36,共8页
Heilongjiang Animal Science And veterinary Medicine
基金
甘肃省自然科学基金项目(22JR5RA742)
国家自然科学基金项目(31960727)。
关键词
鱼类
热应激
抗氧化能力
基因调控
激素分泌
组学技术
fish
heat stress
antioxidant capacity
gene regulation
hormone secretion
omics technoglogy
