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六味地黄汤加味辅助PKP治疗骨质疏松性胸腰椎压缩性骨折临床研究 被引量:3

Clinical Study on Modified Liuwei Dihuang Decoction in Adjuvant Treatment of PKP for Osteoporotic Compression Fracture of Thoracolumbar Spine
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摘要 目的:观察六味地黄汤加味辅助经皮椎体后凸成形术(PKP)治疗肝肾不足型骨质疏松性胸腰椎压缩性骨折的临床疗效。方法:选取72例肝肾不足型骨质疏松性胸腰椎压缩性骨折患者,按随机数字表法分为对照组和观察组,每组36例。研究过程中2组各剔除2例,最终各纳入34例。2组均行PKP治疗,对照组术后予以常规西药治疗,观察组在对照组基础上予以六味地黄汤加味治疗。2组均治疗6周,随访6个月。比较2组临床疗效,术前(治疗前)及术后6周(治疗后)骨密度,Oswestry功能障碍指数(ODI)、视觉模拟评分法(VAS)评分,以及并发症发生率。结果:治疗后,观察组临床疗效总有效率94.12%,与对照组88.24%比较,差异无统计学意义(P>0.05)。2组超声波传播速度(SOS)、T值均较治疗前升高(P<0.05),观察组SOS、T值均高于对照组(P<0.05)。2组VAS、ODI评分均较治疗前降低(P<0.05),观察组VAS、ODI评分均低于对照组(P<0.05)。随访6个月,观察组并发症发生率2.94%,与对照组14.71%比较,差异无统计学意义(P>0.05)。结论:六味地黄汤加味辅助PKP治疗肝肾不足型骨质疏松性胸腰椎压缩性骨折可增强疗效,提高骨密度,缓解临床症状。 Objective:To observe the clinical effect of the therapy of modified Liuwei Dihuang Decoction in adjuvant treatment of percutaneous kyphoplasty(PKP)on osteoporotic compression fracture of thoracolumbar spine of liver and kidney insufficiency type.Methods:A total of 72 patients with osteoporotic compression fracture of thoracolumbar spine of liver and kidney insufficiency type were selected and divided into the control group and the observation group according to the random number table method,with 36 cases in each group.During the study,2 cases dropped off in the two groups,finally 34 cases were included in each group.Both groups were treated with PKP;the control group was treated with conventional western medicine after surgery,and the observation group was additionally treated with modified Liuwei Dihuang Decoction based on the treatment of the control group.Both groups were treated for 6 weeks and followed up for 6 months.The clinical effects,preoperative(before treatment)and 6-week postoperative(after treatment)bone mineral density,Oswestry Disability Index(ODI),Visual Analogue Scale(VAS),and complication rate were compared between the two groups.Results:After treatment,the total clinical effective rate was 94.12%in the observation group and 88.24%in the control group,there being no significant difference(P>0.05).The speed of sound(SOS)and T value in the two groups were increased when compared with those before treatment(P<0.05),and the SOS and T value in the observation group were greater than those in the control group(P<0.05).The scores of VAS and ODI in the two groups were decreased when compared with those before treatment(P<0.05),and the scores of VAS and ODI in the observation group were lower than those in the control group(P<0.05).After 6 months of follow up,the incidence of complications in the observation group was 2.94%,which was not statistically significant when compared with that of 14.71%in the control group(P>0.05).Conclusion:The therapy of modified Liuwei Dihuang Decoction in adjuvant treatme
作者 韩安安 HAN An'an(Pingyang County Hospital of Chinese Medicine,Pingyang Zhejiang 325400,China)
机构地区 平阳县中医院
出处 《新中医》 CAS 2023年第16期56-60,共5页 New Chinese Medicine
关键词 骨质疏松 胸腰椎压缩性骨折 肝肾不足型 经皮椎体后凸成形术 六味地黄汤 骨密度 Osteoporosis Thoracolumbar spine compression fracture Liver and kidney insufficiency type Percutaneous kyphoplasty Liuwei Dihuang Decoction Bone density
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