摘要
目的:调查长沙城区代谢相关脂肪性肝病(MAFLD)患者的主要中医偏颇体质类型及其影响因素。方法:采取分层整群抽样相结合的流行病学调查方法,分析来自长沙市6个城区各500例,共计3000例体检人群中MAFLD患者的中医体质类型,使用logistic回归分析其主要中医偏颇体质类型与BMI、血脂、血糖、血压、尿酸等指标相关性。结果:3000名受调查者符合MAFLD诊断且调查资料完整者779例,其中医体质分布由高到低依次为痰湿质(24.90%,194/779)>平和质(19.26%,150/779)>湿热质(17.84%,139/779)>气虚质(13.74%,107/779)>阴虚质(7.32%,57/779)>特禀质(6.93%,54/779)>阳虚质(5.26%,41/779)>气郁质(3.21%,25/779)>血瘀质(1.54%,12/779),其中痰湿质、湿热质、气虚质、阴虚质和特禀质占比70.73%。性别是痰湿质(P<0.05,OR=0.556,95%CI=0.340~0.911)、湿热质(P<0.05,OR=0.583,95%CI=0.341~0.998)、气虚质(P<0.05,OR=2.075,95%CI=1.240~3.472)的主要影响因素;高血脂是气虚质的主要影响因素(P<0.05,OR=1.524,95%CI=0.999~2.325);高血压(P<0.05,OR=0.495,95%CI=0.272~0.900)、2型糖尿病(P<0.05,OR=0.405,95%CI=0.206~0.799)是阴虚质的主要影响因素。结论:长沙市城区MAFLD患者最常见的5种中医偏颇体质依次为痰湿质、湿热质、气虚质、阴虚质、特禀质;男性MAFLD患者更易出现痰湿质、湿热质、气虚质;高脂血症MAFLD患者更易出现气虚质;高血压、2型糖尿病的MAFLD患者更易出现阴虚质。
Objective:To investigate the main types of TCM biased constitution and its influencing factors in patients with metabolic associated fatty liver disease(MAFLD)in Changsha.Methods:The epidemiological investigation method combining stratified cluster sampling was adopted to analyze the TCM constitution types of MAFLD patients in 3000 physical examination populations from 500 cases in each of the six urban areas of Changsha.The correlation between the main TCM biased constitution types and BMI,blood lipid,blood sugar,blood pressure,uric acid,and other indicators was analyzed by logistic regression.Results:There were 779 cases of 3,000 subjects who met the diagnosis of MAFLD and the investigation data were complete.The TCM constitution distribution of MAFLD from high to low is phlegm-dampness constitution(PDC)(24.90%,194/779)>balanced constitution(BC)(19.26%,150/779)>dampness-heat constitution(DHC)(17.84%,139/779)>qi-deficiency constitution(QDC)(13.74%,107/779)>yin-deficiency constitution(YIDC)(7.32%,57/779)>inherited special constitution(ISC)(6.93%,54/779)>yang-deficiency constitution(YADC)(5.26%,41/779)>qi stagnation constitution(QSC)(3.21%,25/779)>blood stasis constitution(BSC)(1.54%,12/779),including PDC,DHC,QDC,YIDC and ISC accounted for 70.73%.Sex was the main influencing factor of PDC(P<0.05,or=0.556,95%CI=0.340~0.911),DHC(P<0.05,or=0.583,95%CI=0.341~0.998)and DHC(P<0.05,or=2.075,95%CI=1.240~3.472);Hyperlipidemia was the main influencing factor of QDC(P<0.05,or=1.524,95%CI=0.999~2.325);Hypertension(P<0.05,or=0.495,95%CI=0.272~0.900)and type 2 diabetes(P<0.05,or=0.405,95%CI=0.206~0.799)were the main influencing factors of YIDC.Conclusion:The five most common TCM biased constitutions of MAFLD patients in Changsha are PDC,DHC,QDC,YIDC,and ISC;Male MAFLD patients are more prone to PDC,DHC,and QDC;MAFLD patients with hyperlipidemia are more prone to QDC;MAFLD patients with hypertension and type two diabetes are more prone to YIDC.
作者
李红
叶新萍
谭年花
周玉霞
杜珊
陈斌
LI Hong;YE Xin-ping;TAN Nian-hua;CHEN Bin(.The First Affiliated Hospital of Hunan University of Chinese Medicine,(Changsha Hunan,410007),China.)
出处
《中西医结合肝病杂志》
CAS
2023年第9期795-799,共5页
Chinese Journal of Integrated Traditional and Western Medicine on Liver Diseases
基金
湖南省高层次卫生人才“225”工程学科带头人培养项目(湘卫函〔2019〕196号)。
关键词
代谢相关脂肪性肝病
流行病学
中医体质
metabolic associated fatty liver disease
epidemiology
traditional Chinese medicine constitution
