摘要
目的分析β-人绒毛膜促性腺激素(β-HCG)、胎盘生长因子(PGF)及血脂预测孕早期妊娠期高血压疾病的应用价值。方法选取50例妊娠期高血压疾病患者作为试验组;另选取同期50例正常产检孕妇作为参照组。比较两组β-HCG、PGF及血脂指标[总胆固醇(TC)、甘油三酯(TG)、低密度脂蛋白胆固醇(LDL-C)、高密度脂蛋白胆固醇(HDL-C)、载脂蛋白B(ApoB)、载脂蛋白A1(ApoA1)]。结果试验组血清β-HCG指标高于参照组,PGF指标低于参照组,差异有统计学意义(P<0.05)。试验组的TC、TG、LDL-C指标明显高于参照组,HDL-C指标低于参照组,差异有统计学意义(P<0.05),两组ApoA1、ApoB指标比较,差异无统计学意义(P>0.05)。β-HCG、PGF、TC、TG、HDL-C、LDL-C因素均是影响孕早期妊娠期高血压疾病发生的独立因素(P<0.05)。结论β-HCG、PGF、TC、TG、HDL-C、LDL-C均是影响妊娠期高血压疾病的重要因素,联合应用具有更好的预测效果,是妊娠期高血压疾病早期预测的理想监测指标。
Objective To analyze the application value ofβ-human chorionic gonadotropin(β-HCG),placental growth factor(PGF)and blood lipid in predicting hypertensive diseases in early pregnancy.Methods 50 patients with hypertensive disease during pregnancy were selected as the experimental group.Another 50 normal pregnant women were selected as the reference group.Theβ-HCG,PGF and lipid indexes(total cholesterol(TC),triglyceride(TG),low density lipoprotein cholesterol(LDL-C),high density lipoprotein cholesterol(HDL-C),lipid carrying egg white B(ApoB),Apolipoprotein A1(ApoA1))were compared between the two groups.Results Serumβ-HCG index of test group was higher than that of reference group,and PGF index was lower than that of reference group,the difference was statistically significant(P<0.05).The indexes of TC,TG and LDL-C in test group were significantly higher than those in reference group,and the indexes of HDL-C were lower than those in reference group,with statistical significance(P<0.05);there was no statistical significance in ApoAl and ApoB indexes between the two groups(P>0.05).β-HCG,PGE,TC,TG,HDL-C and LDL-C were all independent factors affecting the occurrence of hypertensive diseases in the first trimester of pregnancy(P<0.05).Conclusionβ-HCG,PGF,TC,TG,HDL-C,LDL-C are all important factors affecting hypertensive diseases in pregnancy,and combined application has better prediction effect,and is an ideal monitoring index for early prediction of hypertensive diseases in pregnancy.
作者
杜伟贤
刘翠娴
梁丽仪
温海鹏
Du Weixian;Liu Cuixian;Liang Liyi;Wen Haipeng(Department of Clinical Laboratory,Gaoming District People's Hospital,Foshan 528500,China)
出处
《实用妇科内分泌电子杂志》
2023年第15期99-101,共3页
Electronic Journal of Practical Gynecological Endocrinology
关键词
妊娠期高血压疾病
孕早期
Β-人绒毛膜促性腺激素
胎盘生长因子
Hypertensive diseases during pregnancy
First trimester
β-human chorionic gonadotropin
Placental growth factor
