摘要
目的:探究LAA型脑梗死患者颈动脉斑块稳定性的危险因素。方法:选取75例急性LAA型脑梗死患者为观察组,同期体检健康人群50例作为对照,比较各指标对LAA型脑梗死患者斑块稳定性的诊断价值。结果:不稳定斑块组与稳定斑块组血UA、Hcy、CRP水平及均高于无斑块组及对照组,且斑块积分均高于稳定斑块组(P<0.05);血UA、Hcy、CRP水平及三者联合检测时诊断不稳定斑块的AUC分别为0.816、0.747、0.883、0.915。结论:血UA、Hcy及CRP水平是预测急性LAA型患者颈动脉不稳定性斑块形成及动脉粥样硬化严重程度的可行性指标。
Objective:Exploring risk factors for carotid plaque stability in patients with LAA cerebral infarction.Methods:Seventy-five patients with acute LAA cerebral infarction were selected as the observation group,and 50 healthy patients in the same period of physical examination were used as controls to compare the diagnostic value of each index on plaque stability in patients with LAA cerebral infarction.Results:The levels of UA,Hcy and CRP in the unstable plaque group and the stable plaque group were higher,and the plaque score was higher(P<0.05);the AUC for the diagnosis of unstable plaque was 0.816,0.747,0.883 and 0.915 for blood UA,Hcy,CRP levels and the combination of the three tests,respectively.Conclusion:Blood UA,Hcy and CRP levels are viable predictors of unstable plaque formation and severity of atherosclerosis in carotid arteries in patients with acute LAA.
作者
随旭
朱瑞
丁笑笑
Sui Xu;Zhu Rui;Ding Xiaoxiao(Department of Neurology,The Third Clinical College of Hefei,Anhui Medical University,Hefei 230041,China)
出处
《现代科学仪器》
2023年第4期134-137,共4页
Modern Scientific Instruments
基金
2017年合肥市卫生计生应用医学研究项目(基金编号:hwk2017zc004)。
关键词
脑梗死
大动脉粥样硬化
斑块稳定性
血尿酸
同型半胱氨酸
C-反应蛋白
Cerebral infarction
Large-artery atherosclerosis
Plaque stability
Serum uric acid
Homocysteine
C-reactive protein
