摘要
目的:探讨直肠癌保肛术后患者肠道功能及其影响因素。方法:选择2020年12月至2022年6月于我院行直肠癌保肛手术治疗的100例患者,采用中文版纪念斯隆-凯特林癌症中心(MSKCC)肠道功能问卷评估其术后3个月肠道功能状况,并采集患者一般资料(年龄、性别、家庭常居地、文化程度、婚姻状态、职业、家庭人均月收入水平)及疾病相关临床资料(肿瘤分期、手术方式、吻合方式、肿瘤下缘距肛门距离、放化疗、术后并发症)信息。分析不同特征患者肠道功能差异,对具有统计学意义的指标进一步进行多因素Logistic回归分析,明确影响患者术后肠道功能的独立因素。结果:本组患者术后3个月肠道功能问卷得分平均(65.45±5.48)分。不同年龄、性别、家庭常居地、文化程度、婚姻状态、职业、家庭人均月收入水平,以及不同肿瘤分期、吻合方式患者的肠道功能问卷得分比较差异均无统计学意义(P>0.05),不同手术方式、肿瘤下缘距肛门距离、是否放化疗及是否存在术后并发症组患者肠道功能问卷得分比较差异有统计学意义(P<0.05)。多因素Logistic回归分析显示,手术方式、肿瘤下缘距肛门距离、放化疗、术后并发症是影响直肠癌保肛术后肠道功能的独立因素,P<0.05。结论:直肠癌保肛手术者术后3个月肠道功能处于中等水平,开腹手术、肿瘤下缘距肛门近、术后放化疗及术后存在并发症者肠道功能更差。
Objective To investigate the intestinal function and influencing factors in rectal cancer patients after ano-preserved procedure.Methods Enrolled 100 patients with rectal cancer surgically treated in authors'hospital(2020-12-2022-06)into this research:by using MSKCC questionaire to evaluate the intestinal function status after 3 months of treatment,and to collect patients'common materials(age,gender,family address,educated levels,marrige status,occupation,and monthly income/person)and the disease-related clinical data(oncology stage,procedures,astomy patterns,the distance between anus and lower-edge of tumor,radio-and chemo-therapy,as well as postoperative complication),afterwards,to analyse intestinal function difference among the patients with self-features,for whom having statistical significance,further,to take multi-variate logistic regression analysis so that confirme the independent factors influencing postoperative intestinal function.Results After 3 months of procedures the average ratings on the quenstionaire about intestinal function were(65.45±5.48)points.In above-mentioned common materials and disease-related clinical data;except procedures,the distances between anus and lower-edge of tumor,who with or without radio-and chemo-therapy,as well as who with or without postoperative complication there was statistical difference(P<0.05);other items had no statistical difference between the 100 cases(P<0.05).Multi-variate Logistic regression analysis showed that procedures,the distance of anus from lower-edge of tumor,radio-and chemo-therapy,and,postoperative complication were of independent factors influencing postoperative intestinal function(P<0.05).Conclusion After 3 months of procedure(anus-preserved)in rectal cancer patients their intestinal functions are in moderate level,but when patients receiving open surgery and postoperative radio-and chemo-therapy,and having close distance between anus and lower-edge of tumor,and postoperative complication,the functions more bad.
作者
朱晶晶
张秀真
杨柳
任梅香
ZHU Jing-jing;ZHANG Xiu-zhen;YANG Liu;REN Mei-aiang(Dept.of Oncology,the First Affiliated Hospital of Zhengzhou University,Zhengzhou,Henan 45ooo0)
出处
《中国肛肠病杂志》
2023年第5期45-48,共4页
Chinese Journal of Coloproctology
关键词
直肠癌
保肛术
术后
肠道功能
影响因素
Rectal cancer
Ano-preserved procedure
Post-operation
Intestinal function
Influence factor
