摘要
目的探讨主动脉夹层采用经皮穿刺介入腔内覆膜支架治疗的效果和应用价值。方法选择2021年3月—2022年3月齐齐哈尔医学院附属第三医院收治的50例主动脉夹层患者。以入院先后顺序将患者分组处理,前25例患者设置为对照组行常规药物保守治疗,后25例设置为研究组经皮穿刺介入腔内覆膜支架治疗。统计两组病死率、再手术率。检测两组治疗前后血清炎症指标、肝肾功能指标。对两组患者进行为期1年的随访,记录并发症发生率并评估生活质量评分。结果研究组再手术率为4.00%,低于对照组的24.00%,差异有统计学意义(χ^(2)=4.153,P=0.042)。治疗后研究组血清指标、肝肾功能指标均优于对照组,差异有统计学意义(P<0.05)。随访期间研究组并发症发生率低于对照组,差异有统计学意义(P<0.05)。随访末期,研究组生活质量评分高于对照组,差异有统计学意义(P<0.05)。结论经皮穿刺介入腔内覆膜支架治疗主动脉夹层具备较高的成功率和安全性,能够抑制机体炎症反应,改善肝肾功能,远期生存率、生活质量均较为理想。
Objective To explore the effect and application value of aortic dissection treated with percutaneous punc⁃ture interventional intraluminal coated stent.Methods 50 patients with aortic dissection admitted to the Third Affili⁃ated Hospital of Qiqihar Medical College from March 2021 to March 2022 were selected.The patients were grouped in the order of admission to the hospital,the first 25 patients were set as the control group to be treated conservatively with conventional drugs,and the second 25 patients were set as the study group to be treated with percutaneous punc⁃ture interventional intraluminal coated stent.The morbidity and mortality rate and reoperation rate of the two groups were counted.Serum inflammatory indexes,liver and kidney function indexes were detected before and after treat⁃ment.The patients in the two groups were followed up for one year,and the complication rate was recorded and the quality of life score was evaluated.Results The reoperation rate of the study group was 4.00%,which was lower than that of the control group(24.00%),and the difference was statistically significant(χ^(2)=4.153,P=0.042).After treat⁃ment,the serum indexes and liver and kidney function indexes of the study group were better than those of the control group,and the differences were statistically significant(P<0.05).During the follow-up period,the complication rate ofthe study group was lower than that of the control group,and the difference was statistically significant(P<0.05).At the end of follow-up,the quality of life score of the study group was higher than that of the control group,and the dif⁃ference was statistically significant(P<0.05).Conclusion Percutaneous puncture interventional intraluminal coated stent treatment for aortic dissection has a high success rate and safety,can inhibit the inflammatory response,improve liver and kidney function,and has a better long-term survival rate and quality of life.
作者
赵明宇
赵腾
刘双
李喜春
孟庆宇
于祥文
ZHAO Mingyu;ZHAO Teng;LIU Shuang;LI Xichun;MENG Qingyu;YU Xiangwen(Department of Vascular Surgery,the Third Affiliated Hospital of Qiqihar Medical College,Qiqihar,Heilongjiang Province,161000 China;Department of Critical Care Medicine,the Third Affiliated Hospital of Qiqihar Medical Col-lege,Qiqihar,Heilongjiang Province,161000 China;Department of Academic Affairs,the Third Affiliated Hospital of Qiqihar Medical College,Qiqihar,Heilongjiang Province,161000 China)
出处
《系统医学》
2023年第12期137-140,149,共5页
Systems Medicine
基金
2021年度黑龙江省省属高等学校基本科研业务费科研项目(2021-KYYWF-0353)。
关键词
主动脉夹层
经皮穿刺介入治疗
腔内覆膜支架
临床价值
Aortic dissection
Percutaneous puncture intervention
Intraluminal coated stent
Clinical value
