摘要
目的探讨调神法针刺联合现代康复疗法对男性慢性盆腔疼痛综合征的效果。方法选取2020年10月至2021年10月十堰市太和医院收治的86例男性慢性盆腔疼痛综合征病人,按随机数字表法分为两组。对照组43例采用现代康复疗法治疗,联合组43例给予调神法针刺联合现代康复疗法治疗,两组均治疗4周。采用视觉模拟评分法(VAS)评估比较两组病人治疗前、治疗1周后、2周后、4周后的疼痛情况,对比两组治疗期间急性疼痛发作次数;采用汉密尔顿抑郁量表(HAMD)、汉密尔顿焦虑量表(HAMA)评估比较两组病人治疗前后抑郁和焦虑情绪;对比两组病人治疗前后血清中白细胞介素-6(IL-6)、前列腺素E2(PGE2)、核因子κB(NF-κB)水平的变化及治疗期间不良反应发生情况。结果VAS值在组间、时间、交互方面比较均差异有统计学意义(P<0.05),联合组治疗1周后、2周后、4周后VAS值分别为(3.54±0.65)分、(2.51±0.53)分、(1.86±0.37)分低于对照组相应的VAS值(4.01±0.72)分、(3.04±0.58)分、(2.33±0.44)分;两组治疗后VAS值均低于治疗前(P<0.05),治疗2周后、4周后VAS值均低于1周后(P<0.05),治疗4周后VAS值均低于2周后(P<0.05);治疗后不同时刻联合组VAS值均低于对照组(P<0.05)。联合组治疗期间急性疼痛发作次数低于对照组(P<0.05);治疗后两组HAMD、HAMA评分均较治疗前降低(P<0.05),且联合组均低于对照组(P<0.05)。治疗后两组血清IL-6、PGE2、NF-κB水平均降低(P<0.05),且联合组治疗后血清指标水平均低于对照组(P<0.05);两组不良反应发生率差异无统计学意义(P>0.05)。结论对男性慢性盆腔疼痛综合征病人采取调神法针刺联合现代康复疗法治疗可明显缓解疼痛和改善焦虑、抑郁情绪,降低血清IL-6、PGE2、NF-κB水平,且保障了一定安全性。
Objective To explore the effect of Tiaoshen acupuncture combined with modern rehabilitation therapy on male chronic pelvic pain syndrome.Methods Totally 86 patients with male chronic pelvic pain syndrome treated in Taihe Hospital,Shiyan City from October 2020 to October 2021 were selected and assigned into two groups according to the random number table method.The control group(n=43)were treated with modern rehabilitation therapy,while the combined group(n=43)were treated with Tiaoshen acupuncture combined with modern rehabilitation therapy.Both groups were treated for 4 weeks.Visual analogue scale(VAS)was used to evaluate and compare the pain of the two groups before treatment,1 week,2 weeks,4 weeks after treatment,and the number of acute pain attacks during treatment were compared between the two groups.Hamilton Depression Scale(HAMD)and Hamilton Anxiety Scale(HAMA)were used to evaluate and compare the depression and anxiety of the two groups before and after treatment.The changes of serum levels of interleukin-6(IL-6),prostaglandin E2(PGE2),nuclear factor-κB(NF-κB)before and after treatment and the occurrence of adverse reactions during treatment were compared between the two groups.Results There were significant differences in VAS value among groups,time and interaction(P<0.05).The VAS values of the combined group 1 week,2 weeks and 4 weeks after treatment were(3.54±0.65),(2.51±0.53),and(1.86±0.37)respectively,which were lower than the corresponding VAS values of the control group[(4.01±0.72),(3.04±0.58)and(2.33±0.44),respectively].The VAS values of the two groups after treatment were lower than those before treatment;the VAS values 2 weeks and 4 weeks after treatment were lower than those 1 week after treatment(P<0.05),and the VAS values 4 weeks after treatment were lower than those 2 weeks after treatment(P<0.05).The VAS values of the combined group were lower than those of the control group at different times after treatment(P<0.05).The number of acute pain attacks during treatment in the combined
作者
魏千城
李海峰
WEI Qiancheng;LI Haifeng(Pre-rehabilitation Department,Taihe Hospital,Shiyan,Hubei 442000,China;Nerve Rehabilitation Center,Taihe Hospital,Shiyan,Hubei 442000,China)
出处
《安徽医药》
CAS
2023年第9期1779-1783,共5页
Anhui Medical and Pharmaceutical Journal
基金
湖北省卫生健康委科研项目(ZY2021Q015)。
关键词
慢性盆腔疼痛综合征
调神法针刺
现代康复疗法
男性
负性情绪
炎症
Chronic pelvic pain syndrome
Tiaoshen acupuncture
Modern rehabilitation therapy
Male
Negative emotions
Inflammation
