摘要
百日咳是一种急性呼吸道传染病,各年龄段均易感,成人感染后病程迁延,症状隐匿,易造成家庭传播,婴幼儿感染后易引起重症,因此百日咳仍是重要的公共卫生问题。母亲是婴幼儿的主要传染源,孕期接种百日咳疫苗不仅能降低母体百日咳感染率,母传抗体还能保护婴幼儿,降低婴幼儿百日咳感染率。孕期免疫策略是母体免疫策略之一,作为一种选择性百日咳免疫策略在部分发达国家和中等收入国家已经实施,但我国尚无百日咳疫苗孕期免疫策略,本文对部分国家相关孕期免疫策略研究进展进行综述,旨为我国探索百日咳补充免疫提供依据。
Pertussis is an acute respiratory infectious diseases,which is susceptible in all age groups with prolonged course and obscure symptoms,which easily results in family transmission.Infants and young children are prone to having severe symptom after infection.Therefore,pertussis remains an important public health problem.Pertussis vaccine during pregnancy can not only reduce the maternal pertussis infection rates,but also mother antibody can protect infants and young children and reduce infant pertussis infection rates.Currently maternal immunization during pregnancy as a selective pertussis vaccination strategies in some developed countries and middle income countries.Maternal immunization strategy has not been implemented yet in China.This paper reviews the research progress of maternal immunization strategies for pertussis in order to provide the evidence for exploring our pertussis supplementary immunization strategy.
作者
卢慧子
孙磊
LU Huizi;SUN Lei(Immunization Planning Division,Binhai New Area Center for Disease Control and Prevention,Tianjin 300453,China)
出处
《现代疾病预防控制》
2023年第8期638-642,共5页
MODERN DISEASE CONTROL AND PREVENTION
关键词
百日咳
孕期免疫
免疫策略
研究进展
Pertussis
Maternal immunization during pregnancy
Immunization strategy
Research progress
