摘要
在机体的非特异性免疫系统中,中性粒细胞、淋巴细胞、单核细胞和血小板是重要的组成部分,与组织损伤关系密切,可反映机体的免疫水平。当机体存在严重感染或免疫缺陷时,这些外周血细胞会在功能和数量上出现异常,但在临床中这些指标通常被单独应用。近年来研究发现,中性粒细胞与淋巴细胞比值、血小板与淋巴细胞比值、单核细胞与淋巴细胞比值或淋巴细胞与单核细胞比值等由外周血参数衍生而来的综合指标对于疾病的发生和预后的判断具有预测价值。该文就这些指标在儿童常见疾病中的作用进行综述,为部分疾病的诊断和治疗提供参考。
In the non-specific immune system of human,neutrophils,lymphocytes,monocytes and platelets are important components that play a role in regulating and inducing tissue damage and can reflect the body′s level of immunity.These peripheral blood cells are functionally and quantitatively abnormal in the presence of serious infections or immune deficiencies,but these parameters are usually interpreted in isolation.Recent studies have found that comprehensive indicators derived from peripheral blood parameters,such as neutrophil to lymphocyte ratio,platelet to lymphocyte ratio,monocyte to lymphocyte ratio or lymphocyte to monocyte ratio have predictive value for the occurrence and prognosis of diseases.This article reviews the role of these indicators in common childhood diseases and provides a reference for the diagnosis and treatment of some diseases.
作者
万钟予(综述)
卢燕鸣(审校)
Wan Zhongyu;Lu Yanming(Department of Pediatrics,Renji Hospital,School of Medicine,Shanghai Jiao Tong University,Shanghai 201112,China)
出处
《国际儿科学杂志》
2023年第7期487-491,共5页
International Journal of Pediatrics
