摘要
目的探讨早发型重度子痫前期合并胎儿生长受限(FGR)的妊娠结局。方法选取2019年1月至2021年1月本院收治的96例早发型重度子痫前期患者作为研究对象,根据患者是否合并FGR分为研究组与对照组,每组48例。两组均行期待治疗,比较两组并发症发生情况、期待治疗时间、围生期儿情况、新生儿并发症发生情况,比较研究组不同分娩孕龄的围生期儿结局。结果两组HELLP综合征、子痫、胎盘早剥、心力衰竭、单纯血小板减少、单纯肝功能异常发生率比较差异无统计学意义。两组期待治疗时间比较差异无统计学意义。研究组死亡率高于对照组,出生体质量低于对照组,差异有统计学意义(P<0.05);两组剖宫产率、因胎儿因素终止妊娠率及分娩孕龄比较差异无统计学意义。研究组肺透明膜病发生率低于对照组,心脏发育不全发生率高于对照组,差异有统计学意义(P<0.05);两组新生儿贫血、颅内出血、败血症发生率比较差异无统计学意义。孕龄<30周与孕龄30~31+6周心脏发育不全、新生儿肺透明膜病发生率及围生儿死亡率经比较差异无统计学意义;孕龄≥32周心脏发育不全、新生儿肺透明膜病发生率及围生儿死亡率均低于孕龄<30周、孕龄30~31+6周,差异有统计学意义(P<0.05)。结论期待治疗早发型重度子痫前期伴FGR,不会增加孕产妇的并发症,延长孕周可改善围生期儿结局,降低死亡率。
Objective To investigate the pregnancy outcomes of early onset severe preeclampsia complicated with fetal growth restriction(FGR).Methods 96 patients with early onset severe preeclampsia admitted to our hospital from January 2019 to January 2021 were selected as the research subjects,they were divided into study group and control group according to whether the patients were complicated with FGR,with 48 cases in each group.The two groups were treated with expectant treatment,the incidence of complications,expectant treatment time,perinatal infant condition,and neonatal complications were compared between the two groups,the perinatal infant outcomes of different gestational ages in the study group were compared.Results There was no significant difference in the incidence of HELLP syndrome,eclampsia,placental abruption,heart failure,simple thrombocytopenia,and simple abnormal liver function between the two groups.There was no significant difference in the expectant treatment time between the two groups.The mortality rate of the study group was higher than that of the control group,and the birth weight was lower than that of the control group,and the differences were statistically significant(P<0.05);there were no significant differences in cesarean section rate,termination rate of pregnancy due to fetal factors and gestational age at delivery between the two groups.The incidence of hyaline membrane disease in the study group was lower than that in the control group,and the incidence of cardiac hypoplasia was higher than that in the control group,and the differences were statistically significant(P<0.05).There was no significant difference in the incidence of neonatal anemia,intracranial hemorrhage and sepsis between the two groups.There was no significant difference in the incidence of cardiac hypoplasia,neonatal hyaline membrane disease and perinatal mortality between<30 gestational weeks and 30-31+6 gestational weeks;the incidence of cardiac hypoplasia,neonatal hyalin membrane disease and perinatal mortality of≥
作者
邹路遥
刘长红
王艳
ZOU Luyao;LIU Changhong;WANG Yan(Department of Obstetrical,Tai'an Maternal and Child Health Hospital,Tai'an,Shandong,271000,China;Department of Obstetrical,Tai'an Central Hospital,Tai'an,Shandong,271000,China)
出处
《当代医学》
2023年第13期138-141,共4页
Contemporary Medicine
关键词
早发型重度子痫前期
期待治疗
妊娠结局
胎儿生长受限
Early onset severe preeclampsia
Expectant treatment
Pregnancy outcome
Fetal growth restriction
