摘要
人眼部的各类型细菌在正常情况下可保持动态平衡,对调节宿主代谢,促进免疫系统发育,防御病原体入侵有重要作用;当菌群失衡时则会诱发多种眼部疾病。婴幼儿和儿童由于眼部组织尚未发育完全,抗感染能力较低,受到感染的风险和感染性眼病的进展速度均较高。因此,了解婴幼儿和儿童眼部细菌与眼部疾病发生的关系对疾病的诊断与治疗具有重要意义。本文中笔者汇总比较婴幼儿和儿童眼部健康和疾病状况下眼部细菌的变化,以期为儿童眼病临床诊断治疗和相关研究提供参考。
Various types of bacteria exist in the human eye and maintain a dynamic balance under normal conditions,which is important to regulate host metabolism,promote immune system development,and defend against pathogen invasion.It has been demonstrated that the bacteria species imbalance was associated with various ophthalmic diseases.Infants and children have a higher risk of infection and rate of progression of infectious eye disease than adults due to underdeveloped ocular tissues,lower anti-infective capacity.Therefore,understanding the relationship between the occurrence and development of various ocular diseases and ocular bacteria in infants and children is important for the diagnosis and treatment of the disease.In this paper,the changes of the bacteria of the eye with the ocular health and disease conditions in infants and children were summarized and compared,in order to provide references for clinical diagnosis and treatment and related research.
作者
许皓月
董魁
姬璇
康志明
李俊红
Xu Haoyue;Dong Kui;Ji Xuan;Kang Zhiming;Li Junhong(Department of Ophthalmology,The First Clinical Medical College of Shanxi Medical University,Taiyuan 030001,China)
出处
《中华眼科医学杂志（电子版）》
2023年第2期114-118,共5页
Chinese Journal of Ophthalmologic Medicine(Electronic Edition)
基金
山西省卫生健康委员会青年科研项目(2019076)
山西医科大学附属眼科医院创新基金项目(C202202)。
关键词
眼部菌群
高通量测序
婴幼儿
儿童
眼病
Ocular bacteria species
High throughput sequencing
Infants
Children
Eye diseases
