摘要
目的分析多层螺旋CT在诊断不同分子分型乳腺癌肝转移瘤中的应用价值。方法选取2018年7月至2021年3月我院72例乳腺癌肝转移瘤患者作为研究对象,均行多层螺旋CT诊断。统计Luminal A型、Luminal B型、HER-2过表达型、TNBC型乳腺癌肝转移瘤的影像学特征,包含分布、数目、病灶大小、边界、形态、密度、强化特征情况,分析影像学特征和分子分型的关系、典型案例。结果不同分子分型乳腺癌肝转移瘤分布主要以全肝为主、数目主要以单发为主,但不同分型乳腺癌肝转移瘤分布、数目对比无显著差异(P>0.05);不同分子分型乳腺癌肝转移瘤病灶主要以≤2cm为主,但不同分子分型乳腺癌肝转移瘤对比无显著差异(P>0.05);不同分子分型乳腺癌肝转移瘤边界主要以模糊为主,且Luminal B型模糊者82.14%(184/224)均高于Luminal A型55.56%(20/36)、HER-2过表达型50.23%(107/213)、TNBC型13.10%(19/145)(P<0.05);不同分子分型乳腺癌病灶主要以低密度为主,且Luminal A型97.22%(35/36)、TNBC型96.55%(140/145)均高于Luminal B型58.48%(131/224)、HER-2过表达型54.46%(116/213)(P<0.05);不同分子分型乳腺癌肝转移瘤主要以结节样强化为主,且HER-2过表达型86.85%(185/213)均高于Luminal A型75.00%(27/36)、Luminal B型78.57%(176/224)、TNBC型76.55%(111/145)(P<0.05)。结论多层螺旋CT在不同分子分型乳腺癌肝转移瘤中的诊断价值较高,可促进乳腺癌肝转移瘤的检出率,为疾病确诊提供多方面信息,辅助临床对疾病进行诊疗。
Objective To analyze the application value of multi-slice spiral CT in the diagnosis of liver metastases of breast cancer with different molecular types.Methods 72 patients with liver metastases of breast cancer in our hospital from July 2018 to March 2021 were selected as the research subjects,and all underwent multi-slice spiral CT diagnosis.The imaging features of liver metastases of Luminala type,LuminalB type,Her-2 overexpression type and TNBC type breast cancer were analyzed,including the distribution,number,lesion size,boundary,shape,density and enhancement characteristics,and the relationship between imaging features and molecular typing and typical cases were analyzed.Results The distribution and number of liver metastases of breast cancer with different molecular subtypes were mainly whole liver and single liver,but there was no significant difference in the distribution and number of liver metastases of breast cancer with different subtypes(P>0.05);Different molecular types of breast cancer liver metastases were mainly≤2cm,but there was no significant difference between different molecular types of breast cancer liver metastases(P>0.05);The boundary of liver metastases in different molecular types of breast cancer is mainly fuzzy.In addition,82.14%(184/224)of Luminal B type were higher than 55.56%(20/36)of Luminal A type,50.23%(107/213)of Her-2 overexpression,and 13.10%(19/145)of TNBC type.(P<0.05);Different molecular types of breast cancer focus are mainly low density,Luminal A type 97.22%(35/36)and TNBC type 96.55%(140/145)were higher than Luminal B type 58.48%(131/224)and Her-2 overexpression type 54.46%(116/213)(P<0.05).Different molecular types of breast cancer liver metastases are mainly nodular enhancement.In addition,86.85%(185/213)of HER-2 overexpression was higher than 75.00%(27/36)of Luminal A,78.57%(176/224)of Luminal B and 76.55%(111/145)of TNBC(P<0.05).Conclusion Multi-slice spiral CT has high diagnostic value in different molecular types of liver metastases of breast cancer,which can p
作者
寇文彬
Kou Wen-bin(Shangqiu Traditional Chinese Medicine Hospital,Shangqiu 476000,Henan Province,China)
出处
《罕少疾病杂志》
2023年第8期46-48,共3页
Journal of Rare and Uncommon Diseases
关键词
乳腺癌肝转移瘤
多层螺旋CT
病灶密度
病灶强化特征
Liver Metastases of Breast Cancer
Multislice Spiral CT
Foci Density
Characteristics of Focal Enhancement
