摘要
目的:探究经皮冠状动脉介入手术(PCI)对急性心肌梗死后左室重构及心功能的影响。方法:病例选取海安市人民医院接诊的急性心肌梗死患者160例,病例收集时间为2018年1月至2021年12月。采用随机数表法将患者分为常模组和试验组,各80例。常模组患者入院后未行急诊PCI,以常规药物进行保守治疗,试验组患者入院后行急诊PCI。比较两组治疗前后的心功能指标及血流动力学指标。结果:治疗前,两组的左室收缩末期内径(LVESD)、左室舒张末期内径(LVEDD)、肺动脉平均压(mPAP)、平均二尖瓣压力差(mMPG)对比无统计学差异(P>0.05)。治疗后,试验组的LVESD、LVEDD、mPAP、mMPG均显著低于常模组(P<0.05)。结论:给予急性心肌梗死患者急诊PCI效果良好,能改善心功能和血流动力学指标,延缓左室重构,值得临床推广应用。
Objective:To investigate the effects of percutaneous coronary intervention(PCI)on left ventricular remodeling and cardiac function after acute myocardial infarction.Methods:A total of 160 patients with acute myocardial infarction were selected from Haian People’s Hospital from January 2018 to December 2021.The patients were divided into normal group and experimental group by random number table method,with 80 cases each.Patients in normal mode group did not undergo emergency PCI after admission and were treated conservatively with conventional drugs,while patients in experimental group underwent emergency PCI after admission.The indexes of cardiac function and hemodynamics before and after treatment were compared between the two groups.Results:Before treatment,there were no significant differences in left ventricular end-systolic diameter(LVESD),left ventricular end-diastolic diameter(LVEDD),mean pulmonary artery pressure(mPAP)and mean mitral valve pressure difference(mMPG)between the two groups(P>0.05).After treatment,LVESD,LVEDD,mPAP and mMPG in experimental group were significantly lower than those in normal group(P<0.05).Conclusion:Emergency PCI in patients with acute myocardial infarction has good effect,can improve cardiac function and hemodynamic indexes,delay left ventricular remodeling,and is worthy of clinical application.
作者
陆洋
颜永进
顾顺忠
刘玲玲
缪雄
LU Yang;YAN Yongjin;GU Shunzhong;LIU Lingling;Miao Xiong(Department of Cardiology,Haian People's Hospital,Nantong 226600,China)
关键词
经皮冠状动脉介入手术
急性心肌梗死
左室重构
心功能
血流动力学
percutaneous coronary intervention
Acute myocardial infarction
Left ventricular remodeling
Heart function
hemodynamics
