摘要
目的 分析湖北省400例新型冠状病毒感染恢复期患者半年随访的后遗症特征、证候分布规律及中医证素学特点。方法 通过对760名新型冠状病毒感染恢复期患者的前瞻性随访研究,采集到出院半年后仍有明显后遗症状患者的人口学特征数据与中医四诊资料,提取其中医证候要素,应用频数统计、因子分析、聚类分析等统计学方法,确定其后遗症的存在情况,中医证候、证素及证型的分布规律。结果 随访760例新型冠状病毒感染恢复期患者,其中有400例患者在出院半年后仍有后遗症症状,恢复期最常见的病位证素主要涉及肺、肝、脾、肾等;病性证素主要涉及气虚、阳虚、阴虚、痰、血虚、湿、气滞等。结论 新型冠状病毒感染患者进入恢复期半年后,仍普遍存在多种后遗症症状和诸多身心健康问题。其核心病机可概括为“正虚邪恋”,此时“正虚”以肺、脾、肾三脏亏虚,气阴两虚为主;“邪恋”可表现为肝郁气滞与湿、痰、瘀、热等邪留滞体内。
Objective To analyze characteristics of sequelae,distribution rules of symptoms,and characteristics of syndrome elements of traditional Chinese medicine of 400 corona virus disease 2019(COVID-19)patients in the recovery phase in the half-year follow-up visit.Methods Through the prospective follow-up study on 760 COVID-19 patients in the recovery phase,the data of demographic characteristics and four diagnosis methods of traditional Chinese medicine of patients with obvious sequela symptoms half a year after discharge were collected.Syndrome elements of traditional Chinese medicine were extracted.Frequency statistics,chi-square test,factor analysis,cluster analysis,and other statistical methods were used to determine the existence of sequela,main clinical symptoms,and distribution rules of syndrome elements of traditional Chinese medicine.Results 760 COVID-19 patients in the recovery phase were followed up.Among them,400 patients accord with the definition of post COVID-19 condition,and still had sequela symptoms half a year after discharge.The most common sequela symptoms included weakness,body pain,shortness of breath and weakness,chest distress,etc.The most common syndrome elements of traditional Chinese medicine included lung,liver,spleen,kidney,mind,Qi deficiency,Yang deficiency,Yin deficiency,phlegm,blood deficiency,dampness,Qi stagnation,etc.Conclusion Half a year after COVID-19 patients enter the recovery phase,various sequela symptoms and many physical and mental health problems are common.The core pathogenesis can be summarized as“syndrome of lingering pathogen due to deficient vital Qi”.At this time,“deficient vital Qi”is mainly manifested as lung,spleen,and kidney deficiency and deficiency of both Qi and Yin.“Lingering pathogen”is manifested as stagnation of liver Qi and dampness,phlegm,blood stasis,heat,and other evils leaving in the body.
作者
聂天旸
于会勇
张山
满天
黄振峰
王成祥
NIE Tianyang;YU Huiyong;ZHANG Shan;MAN Tian;HUANG Zhenfeng;WANG Chengxiang(Beijing University of Chinese Medicine Third Clinical Medical College,Beijing 100029,China)
出处
《辽宁中医药大学学报》
CAS
2023年第7期190-196,共7页
Journal of Liaoning University of Traditional Chinese Medicine
基金
北京中医药大学新冠肺炎防控应急专项(2020-JYB-YJ-023)
北京中医药大学一流学科建设项目(20220216)。
关键词
新型冠状病毒感染
恢复期
新型冠状病毒感染后状态
中医证素
corona virus disease 2019
recovery phase
post COVID-19 condition
characteristics of syndrome elements of traditional Chinese medicine
