摘要
目的:基于问卷调查了解口服抗菌药物集中带量采购(简称“集采”)政策实施及临床认可情况现状。方法:通过问卷星平台面向全国多家医疗机构,以口服抗菌药物使用经验丰富科室的医师及临床药师为调查对象开展问卷调查。结果:共收回800份有效问卷,其中医师465名,临床药师335名。支持口服抗菌药物集采政策的受访者占78.8%(630/800),反对该政策受访者比例为5.4%(43/800),主要反对原因为“不支持对抗菌药物设定约定采购量”。348名(43.5%)受访者对本单位口服抗菌药物集采品种及实施细则知晓情况处于中下水平,未对其中7名(0.9%)知晓度差的受访者进行有效性和安全性认可度调查。受访者对集采口服抗菌药物的临床使用频率与其对口服抗菌药物集采政策的支持和知晓情况存在显著关联性(P<0.05)。认可集采品种有效性的受访者占60.9%(483/800),认为集采品种有效性与原研品种存在差异的受访者占39.1%(310/800)。认可集采品种安全性的受访者占80.3%(637/800),医师对安全性的认可度显著高于临床药师(83.9%vs.75.4%,P=0.003)。集采品种有效性和安全性认可情况与受访者所在地域存在显著关联性(P<0.05),华东地区受访者对集采口服抗菌药物的有效性和安全性认可度最低。结论:探索科学的抗菌药物集采约定采购量测算方法,设置合理的抗菌药物临床使用及考评办法;倡导加强集采口服抗菌药物的临床应用监测,鼓励开展基于真实世界数据的集采与原研抗菌药物临床疗效和安全性评价研究,以补充集采口服抗菌药物临床一致性证据,消除公众使用顾虑,提高临床用药信心,推动抗菌药物药品集中带量采购政策深化实施。
OBJECTIVE To understand the status quo of the implementation and clinical recognition of the policy of centralized quantity procurement of oral antibiotics(hereinafter referred to as "collective procurement") based on questionnaire survey.METHODS A questionnaire survey was conducted on the use of oral antimicrobial agents among physicians and clinical pharmacists with rich experience in many medical institutions.RESULTS A total of 800 valid questionnaires were retrieved,including 465 physicians and 335 clinical pharmacists.The percentage of respondents who supported the collective procurement policy of oral antibiotics was 78.8%(630/800),while the percentage of respondents who opposed the policy was 5.4%(43/800).The main reason against the policy was "not supporting the setting of agreed procurement volume of antibiotics".Totally 348(43.5%) interviewees knew the collected varieties of oral antimicrobial drugs and the implementing rules in their own units at the middle or lower level,and no investigation was conducted on the effectiveness and safety recognition in 7(0.88%) interviewees with poor awareness.There was a significant correlation between the frequency of clinical use of oral antibiotics and the support and awareness of oral antibiotics collection policies(P<0.05).The number of interviewees who recognized the effectiveness of the collected varieties was 60.9%(483/800),and the number of interviewees who believed that the effectiveness of the collected varieties was different from that of the original varieties was 39.1%(310/800).The results showed that 80.3%(637/800) of the interviewees approved the safety of collected varieties,and physicians approved the safety significantly more than clinical pharmacists(83.9% vs.75.4%,P=0.003).There was a significant correlation between the recognition of efficacy and safety of the collected varieties and the regions where the interviewees were located(P<0.05),and the interviewees in East China had the lowest recognition of the efficacy and safety of the collected ora
作者
王之舟
董宪喆
白向荣
王可
冯英楠
庄伟
张兰
WANG Zhizhou;DONG Xianzhe;BAI Xiangrong;WANG Ke;FENG Yingnan;ZHUANG Wei;ZHANG Lan(Department of Pharmacy,Xuanwu Hospital of Capital Medical University,Beijing 100053,China)
出处
《中国医院药学杂志》
CAS
北大核心
2023年第13期1506-1511,共6页
Chinese Journal of Hospital Pharmacy
基金
北京市医院管理中心“登峰”计划专项经费资助(编号:DFL20190803)
中国科学技术协会科技智库青年人才计划(编号:20220615ZZ07110070)
首都卫生发展科研专项(首发2022-2Z-20113)。
关键词
国家药品集中采购政策
口服抗菌药物
问卷调查
带量采购
national centralized drug procurement(NCDP)policy
oral antibiotics
questionnaire survey
volume-based pro-curement(VBP)
