摘要
目的研究STEMI患者低血清白蛋白(SA)及不良事件危险因素。方法选取110例STEMI患者,按照SA水平和不良事件情况分为低SA组和高SA组、不良事件组和无不良事件组。分析STEMI患者低SA及发生不良事件的危险因素。结果低SA组年龄、糖尿病、冠心病、心衰、肌酐、全球急性冠状动脉事件登记(GRACE)评分高于高SA组,男性占比、吸烟、血红蛋白、肾小球滤过率(eGFR)低于高SA组(P<0.05)。不良事件组男性占比低于无不良事件组,超敏C反应蛋白、GRACE评分、院内感染、低SA血症高于无不良事件组(P<0.05)。年龄、性别、糖尿病、吸烟、心衰、血红蛋白、肌酐、eGFR和GRACE评分是STEMI患者发生低SA血症的危险因素。低SA与STEMI患者不良事件相关(P<0.05)。性别、超敏C反应蛋白、GRACE评分、院内感染和低SA血症是STEMI患者发生院内不良事件的危险因素。结论低SA与STEMI患者不良事件相关,低SA血症是STEMI患者发生院内不良事件的危险因素。
Aim To study the risk factors of low serum albumin(SA)and adverse events in STEMI patients.Methods A total of 110 patients with STEMI were selected and divided into low SA group,high SA group,adverse event group and no adverse event group according to SA level and adverse event.The risk factors of low SA in STEMI patients and the risk factors of adverse events in STEMI patients were analyzed.Results Low SA age,diabetes mellitus,coronary heart disease,heart failure,creatinine and global registry for acute coronary event(GRACE)scores in the low SA group were higher than those in the high SA group.Percentage of males,smoking,hemoglobin and estimated glomerular filtration rate(eGFR)in the low SA group were lower than those in the high SA group(P<0.05).Percentage of males in the adverse event group was lower than that in the non-adverse event group,and the high-sensitivity C-reactive protein,STEMI nosocomial infection,and low SA hyperlipidemia were higher than those in the non-adverse event group.The differences were statistically significant(P<0.05).Age,gender,diabetes mellitus,smoking,heart failure,hemoglobin,creatinine,eGFR and GRACE score were risk factors for low SA in STEMI patients.Low SA was associated with adverse events in STEMI patients(P<0.05).Gender,high-sensitivity C-reactive protein,GRACE score,nosocomial infection,and low SA were risk factors for in-hospital adverse events in STEMI patients.Conclusion Low SA is associated with adverse events in STEMI patients,and hypo-SA is a risk factor for hospital adverse events in STEMI patients.
作者
梁鹏
卫琪
余道友
LIANG Peng;WEI Qi;YU Daoyou(The Second Department of Cardiology,Traditional Chinese Hospital of Lu'an,Lu'an 237000,Anhui,China)
出处
《中南医学科学杂志》
CAS
2023年第4期568-570,578,共4页
Medical Science Journal of Central South China
基金
安徽省重点研究与开发计划项目(1704f05740)。
