摘要
目的探讨新疆伊犁地区60岁以上农村居民膳食炎症与衰弱的关系。方法2019年1―5月新疆伊犁地区霍城县招募的1682名60岁以上居民为研究对象,进行问卷调查及体格检查,通过能量调整膳食炎症指数(energy-density dietary inflammatory index,EDII)和衰弱指数(frailty index,FI)评价其膳食炎症及衰弱状况,logistic回归分析模型分析膳食炎症与衰弱的关系。结果衰弱前期及衰弱患病率分别为50.65%和8.98%,男性、维吾尔族、文化程度低、家庭年均收入低、单身及体力活动少人群衰弱及衰弱前期患病率较高。EDII与衰弱和衰弱前期均相关,调整性别、民族、家庭年均收入、婚姻状况及体力活动后,随着EDII评分增大衰弱前期和衰弱患病风险有上升趋势(均P趋势<0.05),EDII按三分位数分组的T2、T3组衰弱前期和衰弱患病风险分别是T1组的1.37倍(95%CI:1.04~1.82,P=0.027)和2.18倍(95%CI:1.26~3.76,P=0.005)、1.32倍(95%CI:1.02~1.72,P=0.036)和2.17倍(95%CI:1.28~3.68,P=0.004)。结论膳食炎症与衰弱前期及衰弱相关,膳食可能通过炎症效应参与衰弱的发生发展。
Objective This study aims to investigate the association between dietary inflammation and frailty among rural residents over 60 years old in Yili,Xinjiang.Methods A total of 1682 residents over 60 years old were recruited from Huocheng County,Yili Region,Xinjiang,from January to May,2019.A questionnaire survey and physical examination were conducted.Dietary inflammation and frailty of subjects were evaluated by energy-density dietary inflammatory index(EDII)and frailty index.A logistic regression analysis model was employed to analyze the relationship between dietary inflammation and frailty.Results The prevalence of prefrailty and frailty were 50.65%and 8.97%,respectively.These rates were higher among males,Uygurs,individuals with lower education levels,lower annual family income,those who were divorced,widowed,or unmarried,and subjects who engaged in less physical activity.After adjusting for gender,ethnicity,family annual income,marital status and physical activity,the risk of prefrailty and frailty increased with the EDII score(all Ptrend<0.05).Individuals in EDII tertiles T2(versus T1)were more likely to be pre-frailty(OR=1.37,95%CI:1.04-1.82,P=0.027)and frailty(OR=2.18,95%CI:1.26-3.76,P=0.005).Individuals in EDII T3 also had greater odds of pre-frailty(OR=1.32,95%CI:1.02-1.72,P=0.036)and frailty(OR=2.17,95%CI:1.28-3.68,P=0.004).Conclusions Dietary inflammation is associated with pre-frailty and frailty,and diet may participate in the occurrence and development of frailty through inflammatory effects.
作者
赵辉
符文慧
迪丽胡玛尔·艾力
罗涛
乔婷婷
张国珍
戴江红
ZHAO Hui;FU Wenhui;AILI Dilihumaer;LUO Tao;QIAO Tingting;ZHANG Guozhen;DAI Jianghong(Department of epidemiology and statistics,School of Public Health,Xinjiang Medical University,Urumqi 830017,China;Key Laboratory of Special Environment and Health Research in Xinjiang,Urumqi 830011,China;Institute for immunization planning,Xinjiang Uygur Autonomous Region Center for Disease Control and Prevention,Urumqi 830000,China;Department of Obstetrics and Gynecology Nursing,School of Nursing,Xinjiang Medical University,Urumqi 830017,China)
出处
《中华疾病控制杂志》
CAS
CSCD
北大核心
2023年第6期722-725,共4页
Chinese Journal of Disease Control & Prevention
基金
新疆特殊环境与健康研究重点实验室开发课题(SKL-SEHR-2021-07)
国家自然科学基金(82160640)
国家重点研发计划(2017YFC0907203)。
关键词
新疆
农村居民
膳食炎症
衰弱
Xinjiang
Rural Residents
Dietary inflammatory
Frailty
