摘要
目的 探讨骨骼肌功能测定联合登楼试验对慢阻肺合并非小细胞肺癌患者术后心肺并发症的预测价值。方法 回顾性分析2021年2月—2022年11月我院收治的272例COPD合并肺癌手术患者的资料,根据术后有无心肺并发症分为并发症组、无并发症组。比较两组患者的性别、年龄、吸烟史、骨骼肌功能、登楼试验、肺功能等。并通过Logistic回归分析,检测各指标对术后心肺并发症的预测效力。结果 发生术后心肺并发症的患者共84例(30.9%)。在不同股四头肌力、呼吸肌力、6WMT、吸烟史、登楼试验、DLCO%、FEV_(1)%、△HR、△SpO_(2)、切除范围、手术时间、手术方式、出血量的病例组间发生术后心肺并发症的比例不同(P均<0.05)。回归分析提示,呼吸肌肌力、股四头肌力、6MWT、登楼试验、DLCO%、△HR、△SpO_(2)、手术时间是术后心肺并发症的独立影响因素。结论 骨骼肌功能测定、登楼试验、手术时间及DLCO%可以作为COPD合并肺癌患者的手术风险的评估手段,一定程度上能预测术后心肺并发症的发生,对COPD合并NSCLC术后心肺并发症有预测价值。
Objective To investigate the predictive value of skeletal muscle function test combined with climbing test for postoperative cardiopulmonary complications in patients with chronic obstructive pulmonary disease(COPD)and non-small cell lung cancer(NSCLC).Methods The data of 272 patients with COPD complicated with lung cancer treated in our hospital from February 2021 to November 2022 were retrospectively analyzed.They were divided into the complication group and the non-complication group according to whether there were cardiopulmonary complications after operation.Their sex,age,smoking history,skeletal muscle function,climbing test and lung function of the two groups were compared.Logistic regression analysis was used to test the predictive effect of each index on postoperative cardiopulmonary complications.Results There were 84 patients(30.9%)with postoperative cardiopulmonary complications.The proportion of postoperative cardiopulmonary complications among patients with different quadriceps muscle strength,respiratory muscle strength,6WMT,smoking history,climbing test,D LCO%,FEV_(1)%,△HR,△SpO_(2),resection range,surgical time,surgical method,and bleeding volume was different(P<0.05).Regression analysis showed that respiratory muscle strength,quadriceps muscle strength,6MWT,climbing test,D LCO%,△HR,△SpO_(2) and operation time were independent influencing factors for postoperative cardiopulmonary complications.Conclusion Skeletal muscle function measurement,climbing test,operation time and D LCO%can be used as the means to evaluate the surgical risk of patients with COPD complicated with lung cancer.To some extent,it can predict the occurrence of postoperative cardiopulmonary complications,and has predictive value for the postoperative cardiopulmonary complications of patients with COPD complicated with NSCLC.
作者
贺泽民
魏强
刘柯婷
李红
曹伯雄
昝自亮
冯昊
黄浩
HE Zemin;WEI Qiang;LIU Keting;LI Hong;CAO Boxiong;ZAN Ziliang;FENG Hao;HUANG Hao(Department of Thoracic Surgery,West China Airport Hospital of Sichuan University,Chengdu,Sichuan 610200,China;Department of Neurology,Chengdu Seventh People’s Hospital,Chengdu,Sichuan 610213,China)
出处
《临床肺科杂志》
2023年第8期1169-1173,共5页
Journal of Clinical Pulmonary Medicine
基金
成都市医学科研课题(2022103)。
关键词
慢性阻塞性肺疾病
非小细胞肺癌
术后并发症
骨骼肌功能
登楼试验
chronic obstructive pulmonary disease
non small cell lung cancer
postoperative complications
skeletal muscle function
climbing test
