摘要
目的:探讨药物涂层球囊治疗ST段抬高型急性心肌梗死的临床效果。方法:选取2020年2月—2021年9月上海交通大学医学院附属第九人民医院黄浦分院收治的ST段抬高型急性心肌梗死患者60例为观察对象,根据随机数字表法分为对照组及观察组,各30例。对照组应用药物洗脱支架治疗,观察组应用药物涂层球囊治疗。比较两组治疗效果。结果:术后9个月,两组心功能Ⅲ级、Ⅳ级占比低于术前,Ⅰ级占比高于术前,差异有统计学意义(P<0.05)。观察组心血管不良事件发生率低于对照组,差异有统计学意义(P=0.038)。术后9个月,观察组靶病变血管直径小于对照组,血栓前体蛋白、血管紧张素、氨基末端脑利钠肽前体水平均低于对照组,差异有统计学意义(P<0.05)。观察组手术操作时间短于对照组,差异有统计学意义(P<0.001)。结论:药物涂层球囊对ST段抬高型急性心肌梗死患者的疗效较好,可降低心血管不良事件发生率,缩短手术时间,改善生化指标水平,缩小靶病变血管直径。
Objective:To explore the clinical effect of drug-coated balloon in the treatment of ST-segment elevation acute myocardial infarction.Methods:From February 2020 to September 2021,60 patients with ST-segment elevation acute myocardial infarction who were admitted to the Huangpu Branch of Shanghai Ninth People′s Hospital of Shanghai JiaoTong University School of Medicine were selected as observation objects.They were divided into control group and observation group according to the random number table method,with 30 cases in each group.The control group was treated with drug-eluting stents,and the observation group was treated with drug-coated balloons.The treatment effects of the two groups were compared.Results:At 9 months after surgery,the proportion of cardiac function gradeⅢand gradeⅣin the two groups was lower than that before surgery,and the proportion of gradeⅠwas higher than that before surgery,and the difference was statistically significant(P<0.05).The incidence of adverse cardiovascular events in the observation group was lower than that in the control group,and the difference was statistically significant(P=0.038).At 9 months after surgery,the blood vessel diameter of the target lesion in the observation group was smaller than that in the control group,and the levels of thrombus precursor protein,angiotensin and amino-terminal pro-brain natriuretic peptide in the observation group were lower than those in the control group,and the difference was statistically significant(P<0.05).The operation time in the observation group was shorter than that in the control group,and the difference was statistically significant(P<0.001).Conclusion:The drug-coated balloon has a good effect on patients with ST-segment elevation acute myocardial infarction,it can reduce the incidence of adverse cardiovascular events,shorten the operation time,improve the level of biochemical indexes,and reduce the vascular diameter of the target lesion.
作者
徐宗雨
蒋金全
王晓明
陈奕纬
李宙童
Xu Zongyu;Jiang Jinquan;Wang Xiaoming;Chen Yiwei;Li Zhoutong(Department of Cardiology,Huangpu Branch of Shanghai Ninth People's Hospital,Shanghai JiaoTong University School of Medicine,Shanghai 200011,China)
出处
《中国社区医师》
2023年第19期48-50,53,共4页
Chinese Community Doctors
关键词
药物涂层球囊
急性心肌梗死
心血管不良事件
Drug-coated balloon
Acute myocardial infarction
Adverse cardiovascular events
