摘要
目的评价药物球囊在冠状动脉(冠脉)腔内成形术中治疗小血管病变的疗效和安全性。方法连续入选2016年1月至2017年12月于航天中心医院心脏医学部住院的冠状动脉粥样硬化性心脏病(冠心病)、拟行经皮冠脉介入治疗的患者38例,患者随机分为药物球囊(DCB)治疗组和切割球囊(CBA)治疗组,DCB组应用药物球囊扩张治疗靶病变,CBA组应用切割球囊治疗靶病变,分析比较两组术中即刻效果及远期预后。结果术前两组间临床资料比较无统计学差异;术中两组间均无冠状动脉穿孔、心包填塞、急性血栓事件发生;两组病变血管最小内径(MLD)在术前及术后即刻均无显著差异,随访造影的MLD在DCB组明显优于CBA组(P<0.05);随访期间无死亡、非致死性心梗、血运重建病例。结论在冠脉小血管病变治疗中,药物球囊与切割球囊治疗相比,即刻效果相似,但远期疗效药物球囊更优。
Objective To evaluate the safety and efficacy of drug coated balloon in small coronary arteries.Methods A total of 38 coronary heart disease patients who would undergo percutaneous coronary intervention were enrolled in the study and randomly divided into Drug Coated Balloon(DCB)group(18 cases)and Cutting Balloon Angioplasty(CBA)group(20 cases).The immediate outcomes and long-term efficacy were investigated respectively.Results There was no significant difference in clinical data between the two groups before surgery.There were no coronary perforation,pericardial tamponade and acute thrombosis in the two groups.There was no significant difference between the two groups in minimal lumen diameter(MLD)before and after the operation.The MLD in the follow-up angiography group was significantly better than the CBA group in the DCB group(P<0.05).There was no death or non-lethal during the follow-up period.Sexual myocardial infarction,revascularization cases.Conclusion The immediate outcomes between DCB and CBA were similar in small coronary arteries angioplasty,however,the long-term efficacy of DCB is better than CBA.
作者
翟东东
高炬
张萌
刘鸿宇
王斌
曲涛
Zhai Dongdong;Gao Ju;Zhang Meng;Liu Hongyu;Wang Bin;Qu Tao(Department of Cardiology,The Central Hospital of China Aerospace Corporation,Peking 100049,China)
出处
《中国循证心血管医学杂志》
2019年第4期477-479,共3页
Chinese Journal of Evidence-Based Cardiovascular Medicine
基金
中国航天科工集团公司医疗卫生科研项目(2016-LCYL-005)
