摘要
目的探究头颈部计算机断层扫描血管成像(CTA)联合颅脑灌注(CTP)一站式检查在预测脑梗死预后中的临床价值。方法选取2019年11月-2022年11月广西壮族自治区民族医院和广西壮族自治区人民医院收治的脑梗死患者100例,分为预后良好组68例和预后不良组32例。2组均进行头颈部CTA联合CTP检查并比较相关参数差异;ROC曲线分析CTA、CTP相关参数对脑梗死预后的评估价值。结果预后不良组入院NIHSS评分和入院mRS评分高于预后良好组(P<0.05);预后不良组平均ASPECTS评分、脑血容量(CBV)、脑血流量(CBF)低于预后良好组,ASPECTS评分<5分人数、平均通过时间(MTT)、峰值时间(TTP)高于预后良好组(P<0.05);Pearson相关分析结果显示,ASPECTS评分、CBV、CBF均与NIHSS评分、mRS评分呈负相关,MTT、TTP均与入院NIHSS评分、mRS评分呈正相关(P<0.05);ROC曲线显示,ASPECTS评分、CBV、CBF、MTT、TTP的曲线下面积分别为0.878、0.771、0.870、0.826、0.885,上述指标联合诊断的曲线下面积为0.990(P<0.05)。结论头颈部CTA联合颅脑CTP一站式检查能更好地预测患者预后,值得推广。
Objective To explore the clinical value of head and neck computed tomography angiography(CTA)combined with one-stop examination of craniocerebral computed tomography perfusion(CTP)in predicting the prognosis of cerebral infarction.Methods 100 patients with cerebral infarction who were treated in National Hospital of Guangxi Zhuang Autonomous Region and the People's Hospital of Guangxi Zhuang Autonomous Region from November 2019 to November 2022 were selected and divided into the good prognosis group(68 cases)and the poor prognosis group(32 cases).Both groups underwent head and neck CTA combined with CTP examination,and the differences in related parameters were compared between two groups.Receiver operating characteristic(ROC)curve was used to analyze the evaluated value of related parameters of CTA and CTP in the prognosis of cerebral infarction.Results National Institutes of Health Stroke Scale(NIHSS)score and Modified Rankin Scale(mRS)score at admission in poor prognosis group were higher than those in good prognosis group(P<0.05).In the poor prognosis group the average score of Alberta Stroke Program early CT Score(ASPECTS),cerebral blood volume(CBV)and cerebral blood flow(CBF)were lower than those in good prognosis group(P<0.05),and the number of cases with ASPECTS score less than 5 points,mean transit time(MTT)and time to peak(TTP)were more and longer than those in good prognosis group(P<0.05).Pearson correlation analysis showed that ASPECTS score,CBV and CBF were negatively correlated with NIHSS score and mRS score,and MTT and TTP were positively correlated with NIHSS score and mRS score at admission(P<0.05).ROC curve showed that the area under the curves of ASPECTS score,CBV,CBF,MTT and TTP was 0.878,0.771,0.870,0.826 and 0.885 respectively,and the area under the curve of the combined diagnosis of the above indicators was 0.990(P<0.05).Conclusion Head and neck CTA combined with one-stop examination of craniocerebral CTP can better predict the prognosis of cerebral infarction,and it is worth promoting.
作者
崔香香
何荣新
梁捷凤
王敏莉
乔振虎
CUI Xiangxiang;HE Rongxin;LIANG Jiefeng;WANG Minli;QIAO Zhenhu(National Hospital of Guangxi Zhuang Autonomous Region,Nanning 530000,China;The People's Hospital of Guangxi Zhuang Autonomous Region,Nanning 530000,China)
出处
《长春中医药大学学报》
2023年第7期787-791,共5页
Journal of Changchun University of Chinese Medicine
基金
广西壮族自治区中医药自筹经费科研课题(GXZYZ20210448)。
关键词
脑梗死
预后
头颈部CTA
颅脑灌注一站式检查
cerebral infarction
prognosis
head and neck computed tomography angiography
one-stop examination of craniocerebral perfusion
